Predictive and Preventive Medicine Research Unit, Bambino Gesù Children's Hospital IRCCS, 00165 Rome, Italy.
PhD School of Applied Medical-Surgical Sciences, University of Rome Tor Vergata, 00133 Rome, Italy.
Nutrients. 2023 Jul 20;15(14):3223. doi: 10.3390/nu15143223.
Weight restoration is the primary goal of treatment for patients with Anorexia Nervosa (AN). This observational pilot study aims to describe adherence to the Mediterranean Diet (MD) and the consequent process of weight and functional recovery in outpatient adolescents diagnosed with AN. Eight patients with a median age of 15.1 (14.0-17.1) years were seen at baseline and after six months. Anthropometrics, body composition, and resting energy expenditure (REE) were assessed. The KIDMED questionnaire, the 24 h recall, and a quantitative food frequency questionnaire were used to evaluate adherence to the MD. The median KIDMED score increased from 5.5 (T0) to 10 (T1), which was not significant. Intakes of grams of carbohydrates, lipids, mono-unsaturated fatty acids, and fiber increased ( = 0.012, = 0.036, = 0.036, = 0.025). Weight significantly increased ( = 0.012) as well as lean body mass ( = 0.036), with a resulting improvement of the REE ( = 0.012). No association between anthropometrics and body composition and the KIDMED score was found. The MD could represent an optimal dietary pattern for weight gain and nutritional restoration in patients with AN, and it could lead to an improvement in body composition and resting energy expenditure.
体重恢复是治疗神经性厌食症(AN)患者的主要目标。这项观察性试点研究旨在描述遵守地中海饮食(MD)的情况,以及随之而来的门诊青少年 AN 患者体重和功能恢复的过程。8 名年龄中位数为 15.1 岁(14.0-17.1 岁)的患者在基线和 6 个月时接受了检查。评估了人体测量学、身体成分和静息能量消耗(REE)。使用 KIDMED 问卷、24 小时回顾和定量食物频率问卷评估 MD 的依从性。KIDMED 评分中位数从 5.5(T0)增加到 10(T1),但无统计学意义。碳水化合物、脂肪、单不饱和脂肪酸和纤维的摄入量增加(=0.012、=0.036、=0.036、=0.025)。体重显著增加(=0.012),瘦体重也显著增加(=0.036),REE 随之改善(=0.012)。人体测量学和身体成分与 KIDMED 评分之间没有相关性。MD 可能代表 AN 患者体重增加和营养恢复的最佳饮食模式,它可能导致身体成分和静息能量消耗的改善。