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[孕妇及其子女的乙肝筛查——格赖夫斯瓦尔德围产期-儿科研究]

[Hepatitis B screening in pregnant patients and their children--a Greifswald perinatal-pediatric study].

作者信息

Jährig D, Jülich W D, Heinrich U, Pietsch P, Kombke B

出版信息

Zentralbl Gynakol. 1986;108(12):730-8.

PMID:3751380
Abstract

During a period of one year with systematic screening performed in 1,401 pregnant women 8 cases positive for HBs-antigen could be detected. For the investigation we used a counter electrophoresis method. In 500 serial specimens an additional examination was performed by aid of a RIA as well. With an incidence of 0.57% the number of HBs antigen positive pregnancies in the territory of Greifswald was found to be significantly higher than reported previously from other regions of the GDR. Our results claim for a mass screening for hepatitis B during pregnancy. Because of the possibility of virus excretion with human milk, HBs positive mothers should not be used as milk donors. Other results related to our investigations give evidence for the significance of obtaining specific hygienic regulations when medical care is given to asymptomatic HBsAg carriers. They also underline the necessity of interdisciplinary cooperation for teaching medical staff in health care centers and giving correct advice to those detected as hepatitis B carriers.

摘要

在对1401名孕妇进行了为期一年的系统筛查期间,检测出8例乙肝表面抗原阳性病例。我们采用对流电泳法进行此项调查。在500份连续样本中,还借助放射免疫分析法进行了额外检测。在格赖夫斯瓦尔德地区,乙肝表面抗原阳性妊娠的发生率为0.57%,这一数字明显高于此前民主德国其他地区的报告数据。我们的研究结果呼吁在孕期进行乙肝大规模筛查。鉴于存在通过母乳排出病毒的可能性,乙肝表面抗原阳性的母亲不应作为母乳捐赠者。与我们的调查相关的其他结果表明,在为无症状乙肝表面抗原携带者提供医疗护理时,制定具体卫生规定具有重要意义。这些结果还强调了跨学科合作的必要性,以便在医疗保健中心对医务人员进行培训,并为被检测为乙肝携带者的人提供正确建议。

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