Loi Alicia Siew Ting, Sridhar Revathi, Lim See Ming
Well Programme, Alexandra Hospital, Singapore 159964, Singapore.
Epidemiology Unit, Division of Infectious Diseases, National University Hospital, Singapore 119074, Singapore.
Vaccines (Basel). 2023 Jun 21;11(7):1131. doi: 10.3390/vaccines11071131.
Healthcare workers are recommended to get vaccinated against measles and varicella. This study aims to describe the implementation process of a measles and varicella vaccination program and report on the reduction in the number of susceptible healthcare workers exposed to measles, varicella, and disseminated herpes zoster at a tertiary hospital. The Consolidated Framework for Implementation Research (CFIR) model was used to describe the vaccination program implemented from October 2015 to September 2018. The number of exposed, reviewed, and susceptible healthcare workers during contact tracing for exposure to (a) measles and (b) varicella and disseminated herpes zoster in 2016, 2017, and 2018 is reported. A total of 6770 (95%) out of 7083 healthcare workers completed their immunization review by 2018. In 2016, 20 (10%) out of 198 healthcare workers exposed to measles were considered susceptible. In 2018, no one was found susceptible out of the 51 staff members exposed to measles ( < 0.01). For exposure to varicella and disseminated herpes zoster, seven (5%) out of 154 exposed healthcare workers were susceptible in 2016. In comparison, only two (1%) out of 377 exposed healthcare workers in 2018 were susceptible ( < 0.01). The vaccination program effectively reduced number of healthcare workers susceptible to measles, varicella, and disseminated zoster.
建议医护人员接种麻疹和水痘疫苗。本研究旨在描述麻疹和水痘疫苗接种计划的实施过程，并报告一家三级医院中接触麻疹、水痘和播散性带状疱疹的易感医护人员数量的减少情况。采用实施研究综合框架（CFIR）模型来描述2015年10月至2018年9月实施的疫苗接种计划。报告了2016年、2017年和2018年在接触（a）麻疹和（b）水痘及播散性带状疱疹的接触者追踪期间，暴露、接受检查和易感的医护人员数量。到2018年，7083名医护人员中有6770名（95%）完成了免疫检查。2016年，198名接触麻疹的医护人员中有20名（10%）被认为易感。2018年，在51名接触麻疹的工作人员中未发现易感者（<0.01）。对于接触水痘和播散性带状疱疹的情况，2016年154名暴露的医护人员中有7名（5%）易感。相比之下，2018年377名暴露的医护人员中只有2名（1%）易感（<0.01）。该疫苗接种计划有效减少了对麻疹、水痘和播散性带状疱疹易感的医护人员数量。
