Gylling Annette, Uusi-Rauva Kristiina, Toppila Iiro, Hiltunen-Back Eija
MSD Finland Oy, 02150 Espoo, Finland.
Medaffcon Oy, 02130 Espoo, Finland.
Vaccines (Basel). 2023 Jul 5;11(7):1202. doi: 10.3390/vaccines11071202.
Genital warts (GWs) caused by the human papilloma virus (HPV) are a significant health problem due to high prevalence and rate of recurrence. Bivalent vaccine has been used since the start of the national vaccination program in 2013, making it feasible to study the GW burden in Finland. There is no national and up-to-date information available on the prevalence and the burden of GWs in the various healthcare sectors in Finland. The present study investigated the prevalence, healthcare resource use, and direct medical costs of the treatment of GWs in Finland in 2018 using data in national healthcare registers. GW cases were identified based on diagnoses in public healthcare and GW-related prescription medications. Cost analysis included public healthcare contacts, procedures in private care, and medications. The study showed that approximately 12,000 GWs cases were treated in Finland in 2018. Since less than half of GW diagnoses were recorded in public healthcare registers, determining the exact costs was challenging. The estimated direct treatment costs in 2018 were 2.6 M€, which is higher than the previous estimation in Finland, yet still likely an underestimation of the true burden. These results provide information for the management of the GW burden in Finland.
由人乳头瘤病毒(HPV)引起的尖锐湿疣(GWs)是一个严重的健康问题,因为其患病率和复发率都很高。自2013年国家疫苗接种计划启动以来,二价疫苗就已投入使用,这使得研究芬兰尖锐湿疣的负担成为可能。目前,芬兰各个医疗领域尚无关于尖锐湿疣患病率和负担的全国性最新信息。本研究利用国家医疗登记数据,调查了2018年芬兰尖锐湿疣的患病率、医疗资源使用情况以及治疗的直接医疗费用。尖锐湿疣病例是根据公共医疗保健中的诊断结果以及与尖锐湿疣相关的处方药来确定的。成本分析包括公共医疗接触、私人护理程序和药物。研究表明,2018年芬兰约有12,000例尖锐湿疣病例接受了治疗。由于公共医疗登记中记录的尖锐湿疣诊断病例不到一半,因此确定确切成本具有挑战性。2018年估计的直接治疗费用为260万欧元,高于芬兰此前的估计,但仍可能低估了实际负担。这些结果为芬兰尖锐湿疣负担的管理提供了信息。