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一项估算韩国尖锐湿疣相关疾病负担的横断面研究。

A cross-sectional study estimating the burden of illness related to genital warts in South Korea.

作者信息

Lee Taek Sang, Kothari-Talwar Smita, Singhal Puneet K, Yee Karen, Kulkarni Amit, Lara Nuria, Roset Montserrat, Giuliano Anna R, Garland Suzanne M, Ju Woong

机构信息

Obstetrics and Gynecology, SMG-SNU Boramae Medical Center, Seoul, South Korea.

Outcomes Research, Merck & Co., Inc., Kenilworth, New Jersey, USA.

出版信息

BMJ Open. 2017 Jul 2;7(6):e014217. doi: 10.1136/bmjopen-2016-014217.

Abstract

OBJECTIVES

Estimate the prevalence of genital warts (GW) and GW-related healthcare resource use and costs among male and female patients seeking treatment in South Korea.

DESIGN

To estimate GW prevalence, physicians in five major South Korean regions recorded daily logs of patients (n=71 655) seeking care between July 26 and September 27, 2011. Overall prevalence estimates (and 95% CIs) were weighted by the estimated number of physicians in each specialty and the estimated proportion of total patients visiting each specialist type. Healthcare resource use was compared among different specialties. Corresponding p values were calculated using Mann-Whitney U tests.

SETTING

The database covers 5098 clinics and hospitals for five major regions in South Korea: Seoul, Busan, Daegu, Gwangju and Daejeon.

PARTICIPANTS

Primary care physicians (general practice/family medicine), obstetricians/gynaecologists, urologists and dermatologists with 2-30 years' experience.

RESULTS

The estimated overall GW prevalence was 0.7% (95% CI 0.7% to 0.8%). Among women, GW prevalence was 0.6% (95% CI 0.6% to 0.7%); among men prevalence was 1.0% (95% CI 0.9% to 1.0%), peaking among patients aged 18-24 years. Median costs for GW diagnosis and treatment for male patients were US$58.2 (South Korean Won (KRW) ₩66 857) and US$66.3 (KRW₩76 113) for female patients.

CONCLUSIONS

The estimated overall GW prevalence in South Korea was 0.7% and was higher for male patients. The overall median costs associated with a GW episode were higher for female patients than for male patients.

摘要

目的

估算在韩国寻求治疗的男性和女性患者中尖锐湿疣(GW)的患病率以及与GW相关的医疗资源使用情况和费用。

设计

为估算GW患病率,韩国五个主要地区的医生记录了2011年7月26日至9月27日期间寻求治疗的患者(n = 71655)的每日日志。总体患病率估计值(及95%置信区间)按各专科医生的估计人数以及就诊于每种专科类型的患者总数的估计比例进行加权。比较了不同专科之间的医疗资源使用情况。使用曼-惠特尼U检验计算相应的p值。

背景

该数据库涵盖韩国五个主要地区的5098家诊所和医院:首尔、釜山、大邱、光州和大田。

参与者

具有2至30年经验的初级保健医生(全科/家庭医学)、妇产科医生、泌尿科医生和皮肤科医生。

结果

估计总体GW患病率为0.7%(95%置信区间0.7%至0.8%)。女性中,GW患病率为0.6%(95%置信区间0.6%至0.7%);男性患病率为1.0%(95%置信区间0.9%至1.0%),在18 - 24岁患者中达到峰值。男性患者GW诊断和治疗的中位数费用为58.2美元(66857韩元),女性患者为66.3美元(76113韩元)。

结论

韩国估计的总体GW患病率为0.7%,男性患者患病率更高。女性患者与一次GW发作相关的总体中位数费用高于男性患者。

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