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1967 - 1980年挪威出生队列中的婴儿猝死综合征和围产期后死亡率

Sudden infant death syndrome and post perinatal mortality in Norwegian birth cohorts 1967-1980.

作者信息

Irgens L M, Skjaerven R

出版信息

Acta Paediatr Scand. 1986 Jul;75(4):523-9. doi: 10.1111/j.1651-2227.1986.tb10243.x.

Abstract

The well established effects of maternal age and birth order in sudden infant death syndrome (SIDS) formed the basis for a comparison with other categories of post perinatal death in an attempt to shed some light on the etiologic roles played by ante and postnatal factors. A total of 826,162 children, born 1967 through 1980 and recorded at the Medical Birth Registry of Norway was at risk to die during the post perinatal period (ages 7 through 364 days). Out of the 3,582 infants who died, 1,062 were considered SIDS. Strong effects of maternal age (negative) and birth order (positive) were found in the SIDS group, but not to the same extent in the non-SIDS group or the group of congenital malformations. Likewise, the excess risk in children of unmarried mothers was higher in the SIDS group. The suggested effects of postnatal factors in the causation of SIDS may seem promising from a preventive point of view. The strength of the effects of maternal age and birth order necessitate adjustment for these variables in future epidemiological studies of SIDS.

摘要

母亲年龄和出生顺序在婴儿猝死综合征(SIDS)中已明确的影响,构成了与其他围产期后死亡类别进行比较的基础,旨在试图阐明产前和产后因素所起的病因学作用。1967年至1980年在挪威医疗出生登记处记录的总共826,162名儿童,在围产期后(7至364天)有死亡风险。在3582名死亡婴儿中,1062名被认为是SIDS。在SIDS组中发现了母亲年龄(负向)和出生顺序(正向)的显著影响,但在非SIDS组或先天性畸形组中程度不同。同样,未婚母亲所生孩子的额外风险在SIDS组中更高。从预防的角度来看,产后因素在SIDS病因中所暗示的影响似乎很有前景。母亲年龄和出生顺序影响的强度使得在未来SIDS的流行病学研究中需要对这些变量进行调整。

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