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中国肺结核住院患者非计划性再入院的发生率、原因和危险因素。

Incidence, causes, and risk factors for unplanned readmission in patients admitted with pulmonary tuberculosis in China.

机构信息

The Theorem Clinical College of Wenzhou Medical University, Department of Infectious Disease of Wenzhou Central Hospital, Wenzhou, Zhejiang, China.

Department of Infectious Disease, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

出版信息

J Infect Dev Ctries. 2023 Jul 27;17(7):1007-1013. doi: 10.3855/jidc.17190.

DOI:10.3855/jidc.17190
PMID:37515804
Abstract

INTRODUCTION

To investigate the incidence, causes, and risk factors for unplanned readmission within 30 days of discharge in patients with pulmonary tuberculosis (TB).

METHODOLOGY

The clinical data of 1,062 patients with confirmed pulmonary TB who were admitted to our hospital from October 2018 to October 2021 were analysed retrospectively. The subjects were divided into a readmission group (354 cases) and a non-readmission group (708 cases) according to whether there was an unplanned admission within 30 days of discharge. We analysed the risk factors for unplanned readmission within 30 days after discharge with pulmonary TB.

RESULTS

The incidence of unplanned readmission in patients with pulmonary TB was 5.2%. Being female (OR = 0.63, 95% CI: 0.434-0.942) and living in cities (OR = 0.218, 95% CI: 0.151-0.315) were protective factors for the readmission of patients with TB (p < 0.05). However, being ≥ 65 years old (OR = 2.574, 95% CI: 1.709-3.870), being a smoker (OR = 2.773, 95% CI: 1.751-4.390), having chronic obstructive pulmonary disease (COPD) (OR = 3.373, 95% CI: 1.708-6.660), having viral hepatitis (OR= 2.079, 95% CI: 1.067-4.052), receiving non-standard treatment (OR = 15.620, 95% CI: 10.413-23.431), having medical side effects (OR = 6.138, 95% CI: 3.798-9.922) and l unauthorised discharge (OR = 2.570, 95% CI: 1.509-4.376) were risk factors for the readmission to hospital of patients with TB (p < 0.05).

CONCLUSIONS

Gender, age, place of residence, smoking, COPD, hepatitis, non-standard treatment, adverse drug reactions and unauthorised discharge were risk factors of TB for unplanned readmission.

摘要

目的

调查出院后 30 天内肺结核(TB)患者计划性再入院的发生率、原因和危险因素。

方法

回顾性分析 2018 年 10 月至 2021 年 10 月我院收治的 1062 例确诊肺结核患者的临床资料,根据出院后 30 天内是否计划性再入院将患者分为再入院组(354 例)和非再入院组(708 例)。分析肺结核患者出院后 30 天内计划性再入院的危险因素。

结果

肺结核患者计划性再入院发生率为 5.2%。女性(OR=0.63,95%CI:0.434-0.942)和城市居住(OR=0.218,95%CI:0.151-0.315)是结核病患者再入院的保护因素(p<0.05)。而年龄≥65 岁(OR=2.574,95%CI:1.709-3.870)、吸烟(OR=2.773,95%CI:1.751-4.390)、慢性阻塞性肺疾病(COPD)(OR=3.373,95%CI:1.708-6.660)、病毒性肝炎(OR=2.079,95%CI:1.067-4.052)、接受非标准治疗(OR=15.620,95%CI:10.413-23.431)、药物不良反应(OR=6.138,95%CI:3.798-9.922)和擅自离院(OR=2.570,95%CI:1.509-4.376)是结核病患者再入院的危险因素(p<0.05)。

结论

性别、年龄、居住地、吸烟、COPD、肝炎、非标准治疗、药物不良反应和擅自离院是结核病患者计划性再入院的危险因素。

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