Feng Yinping, Guo Jing, Luo Shuirong, Zhang Zunjing, Liu Zhongda
Department of Tuberculosis, Lishui Hospital of Traditional Chinese Medicine Affiliated to Zhejiang University of Traditional Chinese Medicine, Lishui Tuberculosis Clinical Medical Research Center, Lishui, Zhejiang, People's Republic of China.
Infect Drug Resist. 2024 Apr 26;17:1625-1632. doi: 10.2147/IDR.S459260. eCollection 2024.
Exploring the risk factors for readmission of elderly patients with pulmonary tuberculosis (PTB) within one month using the propensity score matching(PSM).
A retrospective analysis was conducted on the clinical data of elderly patients with PTB who were admitted to the Tuberculosis Department of Lishui Hospital of Traditional Chinese Medicine from January 2020 to October 2023. The patients were divided into two groups: non-readmission group and readmission group based on whether they were readmitted within one month after discharge. The PSM method was used to match the baseline data of the two groups of patients, and multivariate logistic regression analysis was conducted to explore the risk factors for readmission of elderly patients with PTB within one month after discharge.
A total of 1268 hospitalized elderly patients with PTB were included in the study, comprising 977 readmitted patients and 291 newly admitted patients (22.95%). Using the PSM, 288 pairs of patients were successfully matched. Following matching, there were no statistically significant differences between the two groups in terms of gender, age, occupation, body mass index(BMI), past medical history, etc. (all >0.05). Multivariate logistic regression analysis indicated that infection, drug-induced liver injury(DILI), acute heart failure(AHF), chronic kidney disease(CKD), and extrapulmonary tuberculosis(EPTB) were all identified as risk factors for readmission of elderly patients with PTB.
After controlling for confounding factors through PSM, the study revealed that infection, DILI, AHF, CKD, and EPTB are risk factors for readmission among elderly patients with PTB, highlighting the need for early intervention.
采用倾向得分匹配法（PSM）探讨老年肺结核（PTB）患者出院1个月内再入院的危险因素。
回顾性分析2020年1月至2023年10月丽水市中医院结核科收治的老年PTB患者的临床资料。根据患者出院后1个月内是否再次入院分为非再入院组和再入院组。采用PSM法对两组患者的基线数据进行匹配，并进行多因素logistic回归分析，以探讨老年PTB患者出院后1个月内再入院的危险因素。
本研究共纳入1268例住院老年PTB患者，其中再入院患者977例，新入院患者291例（22.95%）。通过PSM成功匹配了288对患者。匹配后，两组患者在性别、年龄、职业、体重指数（BMI）、既往病史等方面差异均无统计学意义（均>0.05）。多因素logistic回归分析表明，感染、药物性肝损伤（DILI）、急性心力衰竭（AHF）、慢性肾脏病（CKD）和肺外结核（EPTB）均为老年PTB患者再入院的危险因素。
通过PSM控制混杂因素后，本研究表明感染、DILI、AHF、CKD和EPTB是老年PTB患者再入院的危险因素，强调了早期干预的必要性。
