Salazar-Méndez Joaquín, Núñez-Cortés Rodrigo, Suso-Martí Luis, Ribeiro Ivana Leão, Garrido-Castillo María, Gacitúa José, Mendez-Rebolledo Guillermo, Cruz-Montecinos Carlos, López-Bueno Rubén, Calatayud Joaquín
Escuela de Kinesiología, Facultad de Salud, Universidad Santo Tomás, Talca, Chile.
Physiotherapy in Motion Multispeciality Research Group (PTinMOTION), Department of Physiotherapy, University of Valencia, Valencia, Spain; Department of Physical Therapy, Faculty of Medicine, University of Chile, Santiago, Chile.
Neurosci Biobehav Rev. 2023 Oct;153:105328. doi: 10.1016/j.neubiorev.2023.105328. Epub 2023 Jul 27.
The aim was to examine the moderator effect of duration of PNE (total minutes) on changes in psychosocial variables after treatment in people with chronic musculoskeletal pain. PubMed/MEDLINE, Embase, Web of Science, Scopus and CINHAL databases were systematically searched from inception to 6 February 2023. A mixed-effects meta-regression was performed to determine the moderator effect of PNE duration. Twenty-three studies involving 2352 patients were included. Meta-analysis revealed a statistically significant effect in favour of PNE on pain neurophysiology knowledge, anxiety symptoms, catastrophizing and kinesiophobia. The total duration of PNE ranged from 40 to 720 min. A linear relationship was observed between longer duration of PNE (total minutes) and changes of psychosocial variables. In addition, a dose of 100, 200 and 400 min of PNE was estimated to exceed the minimum clinically important difference described in the literature for kinesiophobia (mean difference = -8.53 points), anxiety symptoms (mean difference = -1.88 points) and catastrophizing (mean difference = -7.17 points). Clinicians should provide a more tailored PNE to address psychosocial variables.
目的是研究慢性肌肉骨骼疼痛患者治疗后，疼痛神经电刺激（PNE，总分钟数）持续时间对心理社会变量变化的调节作用。对PubMed/MEDLINE、Embase、Web of Science、Scopus和CINHAL数据库进行了系统检索，检索时间从建库至2023年2月6日。进行了混合效应元回归分析以确定PNE持续时间的调节作用。纳入了23项研究，涉及2352例患者。荟萃分析显示，PNE在疼痛神经生理学知识、焦虑症状、灾难化思维和运动恐惧方面有统计学意义上的显著效果。PNE的总持续时间为40至720分钟。观察到较长的PNE持续时间（总分钟数）与心理社会变量的变化之间存在线性关系。此外，估计100、200和400分钟的PNE剂量超过了文献中描述的运动恐惧（平均差值=-8.53分）、焦虑症状（平均差值=-1.88分）和灾难化思维（平均差值=-7.17分）的最小临床重要差异。临床医生应提供更具针对性的PNE来解决心理社会变量问题。
