Department of Gastroenterology, MedStar Georgetown University Hospital, 3800 Reservoir Road Northwest, Washington, DC 20007, USA.
Baltimore, MD, USA.
Prim Care. 2023 Sep;50(3):363-376. doi: 10.1016/j.pop.2023.03.007. Epub 2023 May 16.
Abnormal liver tests are one of the most common challenges in the primary care setting. Primary care practitioners order these tests for numerous reasons, including investigating abdominal signs and symptoms or suspected alcohol-use disorder, or to determine medication adverse effects. Evaluation should be guided by both the clinical presentation and the pattern of injury. In this article, we will focus on the epidemiology, pathophysiology, clinical presentation, diagnostic work-up, and management of elevated liver enzymes, with an emphasis on the most common causes of abnormal liver testing.
异常的肝功能检查是基层医疗环境中最常见的挑战之一。基层保健医生出于多种原因开这些检查，包括检查腹部体征和症状或疑似酒精使用障碍，或确定药物的不良反应。评估应同时根据临床表现和损伤模式进行。在本文中，我们将重点介绍肝酶升高的流行病学、病理生理学、临床表现、诊断方法和管理，重点介绍异常肝功能检查最常见的原因。
