CRISPR 增强型生物传感器在无扩增核酸检测中的研究进展。
Evolution of CRISPR-enabled biosensors for amplification-free nucleic acid detection.
机构信息
School of Chemical and Biomolecular Engineering, The University of Sydney, Sydney, NSW 2006, Australia; Nano Institute (Sydney Nano), The University of Sydney, Sydney, NSW 2006, Australia.
School of Chemical and Biomolecular Engineering, The University of Sydney, Sydney, NSW 2006, Australia; Nano Institute (Sydney Nano), The University of Sydney, Sydney, NSW 2006, Australia.
出版信息
Trends Biotechnol. 2024 Jan;42(1):10-13. doi: 10.1016/j.tibtech.2023.07.004. Epub 2023 Jul 27.
CRISPR biosensors enable rapid and accurate detection of nucleic acids without resorting to target amplification. Specifically, these systems facilitate the simultaneous detection of multiple nucleic acid targets with single-base specificity. This is an invaluable asset that can ultimately facilitate accurate diagnoses of biologically complex diseases.
CRISPR 生物传感器无需依赖靶标扩增即可实现对核酸的快速准确检测。具体而言，这些系统能够以单碱基特异性实现对多个核酸靶标的同时检测。这是一项非常宝贵的资产，最终可以促进对生物复杂性疾病的准确诊断。
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