Department of Psychiatry, Wroclaw Medical University, Pasteura 10 Street, 50-367, Wroclaw, Poland.
Experimental Psychopathology Lab, Institute of Psychology, Polish Academy of Sciences, Warsaw, Poland.
Eur Arch Psychiatry Clin Neurosci. 2024 Mar;274(2):255-263. doi: 10.1007/s00406-023-01653-3. Epub 2023 Jul 30.
Psychotic-like experiences (PLEs) have been associated with poor sleep quality and increased suicide risk. However, the association between PLEs, insomnia and suicide risk has not been thoroughly investigated in prior studies. In this study, we aimed to explore as to whether insomnia moderates the association between PLEs and suicidal ideation. The study was performed in 4203 young adults (aged 18-35 years, 63.8% females). Data were collected using self-reports. Moderation analysis demonstrated that PLEs are associated with higher levels of the current suicidal ideation only in participants with greater severity of insomnia (B = 0.003, p < 0.001). This analysis included age, gender, education, occupation and depressive symptoms as covariates. Moreover, the network analysis demonstrated that nodes representing PLEs are connected to the node of current suicidal ideation only in participants with greater severity of insomnia. The nodes of PLEs connected to the current suicidal ideation node captured PLEs representing deja vu experiences, auditory hallucination-like experiences and paranoia (edge weights between 0.011 and 0.083). Furthermore, nodes representing PLEs were the three most central nodes in the network analysis of individuals with higher levels of insomnia (strength centrality between 0.96 and 1.10). In turn, the three most central nodes were represented by depressive symptoms in the network analysis of individuals with lower levels of insomnia (strength centrality between 0.67 and 0.79). Findings from this study indicate that insomnia might be an important risk factor of suicide in people with PLEs, especially those reporting deja vu experiences, auditory hallucination-like experiences and paranoia.
精神病样体验(PLEs)与睡眠质量差和自杀风险增加有关。然而,在之前的研究中,PLEs、失眠和自杀风险之间的关联尚未得到彻底研究。在这项研究中,我们旨在探讨失眠是否调节了 PLEs 与自杀意念之间的关系。该研究在 4203 名年轻成年人(18-35 岁,63.8%为女性)中进行。数据通过自我报告收集。调节分析表明,只有在失眠严重程度较高的参与者中,PLEs 与当前自杀意念的水平升高相关(B=0.003,p<0.001)。该分析包括年龄、性别、教育、职业和抑郁症状作为协变量。此外,网络分析表明,仅在失眠严重程度较高的参与者中,代表 PLEs 的节点与当前自杀意念的节点相连。代表 PLEs 的节点与当前自杀意念节点相连,仅代表失眠严重程度较高的参与者中出现的即视体验、类似听觉幻觉的体验和偏执(节点之间的边权重在 0.011 和 0.083 之间)。此外,在失眠程度较高的个体的网络分析中,代表 PLEs 的节点是三个最中心的节点(强度中心度在 0.96 和 1.10 之间)。相反,在失眠程度较低的个体的网络分析中,三个最中心的节点由抑郁症状表示(强度中心度在 0.67 和 0.79 之间)。本研究的结果表明,失眠可能是 PLEs 患者自杀的一个重要危险因素,尤其是那些报告即视体验、类似听觉幻觉的体验和偏执的患者。