Arakawa S, Kamidono S, Ishigami J, Kawamura N, Ohkoshi M, Ban Y, Nishiura T, Kumamoto Y, Kishi H, Kawada Y
Hinyokika Kiyo. 1986 May;32(5):697-711.
The recurrence of female acute uncomplicated cystitis was investigated clinically. The criteria for the evaluation of recurrences were proposed, as follows;
Target infection is acute uncomplicated cystitis (AUC) which had satisfied the specifications of AUC Criteria by the UTI Committee of Japan and showed the excellent effects of an antimicrobial agent after a definite period of administration. Treatment period: Seven days; after 3 days' administration to evaluate the drug efficacy, patients shall take an additional 4 days' treatment. Interval of follow up proposed was 7 days. Evaluation of recurrence: Parameters of criteria are pyuria and bacteriuria. Recurrence: Pyuria greater than or equal to 10 WBCs/hpf and bacteriuria greater than or equal to 10(4)/ml. Evaluation of the day of recurrence: Evaluation should be made 14 days after the start of treatment. Urine sampling: After 7 days of treatment, midstream urine is collected and in cases with positive findings, catheterized urine should then be collected. Using these criteria it will be possible to evaluate and compare the ability of various antimicrobial agents to cure acute uncomplicated cystitis.
对女性急性单纯性膀胱炎的复发情况进行了临床研究。提出了评估复发的标准如下:
目标感染为急性单纯性膀胱炎(AUC),其符合日本UTI委员会制定的AUC标准规范,且在一定疗程的抗菌药物治疗后显示出良好疗效。治疗周期:7天;给药3天后评估药物疗效,患者需额外接受4天治疗。建议的随访间隔为7天。复发评估:评估标准参数为脓尿和菌尿。复发:脓尿≥10个白细胞/高倍视野且菌尿≥10⁴/ml。复发日评估:应在治疗开始后14天进行评估。尿液采样:治疗7天后收集清洁中段尿,若结果为阳性,则随后收集导尿尿液。使用这些标准将能够评估和比较各种抗菌药物治愈急性单纯性膀胱炎的能力。