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日本首例儿童多系统炎症综合征(MIS-C)致暴发性心肌炎并需要机械循环支持的病例。

The First Case in Japan of Fulminant Myocarditis Due to Multisystem Inflammatory Syndrome in Children (MIS-C) That Required Mechanical Circulatory Support.

机构信息

Center of Postgraduate Training, Nara Medical University.

Department of Pediatrics, Nara Medical University.

出版信息

Int Heart J. 2023;64(4):783-788. doi: 10.1536/ihj.23-116.

Abstract

Multisystem inflammatory syndrome in children (MIS-C) is a novel hyperinflammatory syndrome that is associated with severe acute respiratory syndrome coronavirus 2 infections. Reports describing the mechanical circulatory support (MCS) and myocardial biopsy for fulminant myocarditis due to MIS-C are limited.A 13-year-old male patient with MIS-C underwent treatment, including immunosuppressive therapy and MCS devices, and managed to recover from pulseless electrical activity cardiac arrest.This is the first patient in Japan with MIS-C who required MCS devices in Japan. Appropriate and immediate treatment with immunosuppressive therapy and MCS devices is important.

摘要

儿童多系统炎症综合征(MIS-C)是一种与严重急性呼吸综合征冠状病毒 2 感染相关的新型超炎症综合征。描述因 MIS-C 导致的暴发性心肌炎采用机械循环支持(MCS)和心肌活检的报告有限。一位 13 岁男性 MIS-C 患者接受了治疗,包括免疫抑制治疗和 MCS 设备,并且成功从无脉性电活动心脏骤停中恢复。这是日本首例需要 MCS 设备的 MIS-C 患者。采用免疫抑制治疗和 MCS 设备进行适当和及时的治疗很重要。

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