Division of Urology, Department of Surgery, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.
Pediatr Nephrol. 2024 Feb;39(2):409-421. doi: 10.1007/s00467-023-06064-z. Epub 2023 Jul 31.
Neurogenic bladder (NGB) is an encompassing term that includes multiple causes of bladder dysfunction linked to a congenital or acquired neurological condition that adversely impacts the innervation of the lower urinary tract. Multiple static or progressive conditions can be associated with NGB in pediatric and adolescent patients. Currently, spinal dysraphism (i.e., spina bifida) is one of the most common etiologies, which occurs in 3-4 per 10,000 live births in developed nations. Abnormal bladder dynamics can lead to kidney damage secondary to high pressures or recurrent infections, as well as urinary incontinence. The current management paradigm centers on a proactive approach to preserving kidney function and achieving continence through behavioral, pharmacological, and surgical means. This educational review highlights the key components of urological management to maximize collaboration with pediatric nephrologists.
神经源性膀胱（NGB）是一个包含多个术语的统称，这些术语涉及多种与先天或后天神经状况相关的膀胱功能障碍，这些状况会对下尿路的神经支配产生不利影响。在儿科和青少年患者中，多种静态或进行性疾病都可能与 NGB 相关。目前，脊髓脊膜膨出（即脊柱裂）是最常见的病因之一，在发达国家每 10000 例活产中就有 3-4 例。异常的膀胱动力学可导致肾脏因高压或反复感染而受损，以及尿失禁。目前的管理模式侧重于通过行为、药物和手术手段积极保护肾功能和实现控尿。本教育综述强调了泌尿外科管理的关键组成部分，以最大限度地与儿科肾病医生合作。
