针刺对缺血性脑卒中程序性细胞死亡影响的研究进展

[Research progress of the impacts of acupuncture on programmed cell death in treatment of ischemic stroke].

作者信息

Feng Ya-Shuo, Wu Yi, Wang Nian-Hong

机构信息

School of Rehabilitation Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; Department of Rehabilitation Medicine, Huashan Hospital Affiliated to Fudan University, National Center for Neurological Disorders, Shanghai 200040.

Department of Rehabilitation Medicine, Huashan Hospital Affiliated to Fudan University, National Center for Neurological Disorders, Shanghai 200040.

出版信息

Zhen Ci Yan Jiu. 2023 Jul 25;48(7):713-7. doi: 10.13702/j.1000-0607.20220404.

DOI:10.13702/j.1000-0607.20220404

PMID:37518967

Abstract

The new progress has been made in the research of programmed cell death (e.g. autophagy, apoptosis, pyroptosis, necroptosis and ferroptosis) for the pathological mechanism of ischemic stroke. As an important non-pharmacological therapy, acupuncture is widely used in stroke patients and has achieved favorable effect. The researches in recent years have shown that acupuncture plays its neuroprotective role on ischemic stroke by modulation of autophagy, apoptosis, pyroptosis, necroptosis and ferroptosis of neurons. Acupuncture is effective in treatment of ischemic stroke by regulating programmed cell death.

摘要

在缺血性中风病理机制的研究中，程序性细胞死亡（如自噬、凋亡、焦亡、坏死性凋亡和铁死亡）方面取得了新进展。作为一种重要的非药物治疗方法，针灸在中风患者中广泛应用并取得了良好效果。近年来的研究表明，针灸通过调节神经元的自噬、凋亡、焦亡、坏死性凋亡和铁死亡发挥其对缺血性中风的神经保护作用。针灸通过调节程序性细胞死亡对缺血性中风治疗有效。