2'-脱氧-2'-氟尿苷-5'-三磷酸：大肠杆菌RNA聚合酶的一种可能底物。
2'-Deoxy-2'-fluorouridine-5'-triphosphates: a possible substrate for E. coli RNA polymerase.
作者信息
Pinto D, Sarocchi-Landousy M T, Guschlbauer W
出版信息
Nucleic Acids Res. 1979 Mar;6(3):1041-8. doi: 10.1093/nar/6.3.1041.
Abstract
dUflTP was tested as substrate in the E. coli RNA polymerase system using poly(dAT) as template. dUflTP could replace UTP when Mn++ was utilized as divalent cation instead of Mg++. The level of transcription with the fluoro analog was then 55% of that with UTP.
摘要
以聚（dAT）为模板，在大肠杆菌RNA聚合酶系统中测试了dUflTP作为底物的情况。当使用Mn++作为二价阳离子而非Mg++时，dUflTP可以替代UTP。然后，使用这种含氟类似物时的转录水平为使用UTP时的55%。
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