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经鼻直接穿刺术前奥尼克斯栓塞术在晚期青少年鼻咽血管纤维瘤治疗中的作用

The Role of Preoperative Onyx Embolization by Transnasal Direct Puncture in the Treatment of an Advanced Juvenile Nasopharyngeal Angiofibroma.

作者信息

Hilton Vieira Madeira Tiago, Meneghelli Galvão Gonçalves Augusto, Viguini Tolentino Correa Amanda, Oliveira Ramalho Clauder, Nascimento Ottoni Alexandre

机构信息

Neurosurgery and Interventional Neuroradiology, Hospital Santa Rita de Cássia, Vitória, BRA.

Interventional Neuroradiology, Hospital Santa Rita de Cássia, Vitória, BRA.

出版信息

Cureus. 2023 Jun 26;15(6):e40984. doi: 10.7759/cureus.40984. eCollection 2023 Jun.

DOI:10.7759/cureus.40984
PMID:37519490
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10372519/
Abstract

Juvenile nasopharyngeal angiofibroma (JNA) is a rare and locally aggressive tumor that commonly presents with painless nasal obstruction and severe, recurrent epistaxis. In this case report, we describe the successful management of a Radkowski stage IIIA JNA with extensive arterial supply from the internal carotid artery (ICA). Transnasal direct puncture embolization using Onyx (Medtronic, Minneapolis, Minnesota) was employed to effectively devascularize the tumor, enabling radical surgical resection in a single piece via endonasal and transmaxillary endoscopic approaches. The patient did not require blood transfusion and was discharged without neurological impairment. The effectiveness of preoperative embolization as a treatment strategy for JNA is also discussed.

摘要

青少年鼻咽血管纤维瘤(JNA)是一种罕见的、具有局部侵袭性的肿瘤,通常表现为无痛性鼻塞和严重的反复鼻出血。在本病例报告中,我们描述了一例Radkowski IIIA期JNA的成功治疗,该肿瘤由颈内动脉(ICA)提供广泛的动脉血供。采用Onyx(美敦力公司,明尼阿波利斯,明尼苏达州)经鼻直接穿刺栓塞术有效使肿瘤血管减少,从而能够通过鼻内和经上颌窦内镜手术整块切除肿瘤。患者无需输血,出院时无神经功能损害。我们还讨论了术前栓塞作为JNA治疗策略的有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b047/10372519/32be4b504da1/cureus-0015-00000040984-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b047/10372519/77e964138869/cureus-0015-00000040984-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b047/10372519/c61b0fd71351/cureus-0015-00000040984-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b047/10372519/85be8955bafc/cureus-0015-00000040984-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b047/10372519/206690d0c84a/cureus-0015-00000040984-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b047/10372519/32be4b504da1/cureus-0015-00000040984-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b047/10372519/77e964138869/cureus-0015-00000040984-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b047/10372519/c61b0fd71351/cureus-0015-00000040984-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b047/10372519/85be8955bafc/cureus-0015-00000040984-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b047/10372519/206690d0c84a/cureus-0015-00000040984-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b047/10372519/32be4b504da1/cureus-0015-00000040984-i05.jpg

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本文引用的文献

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Otolaryngol Head Neck Surg. 2023 Sep;169(3):454-466. doi: 10.1002/ohn.303. Epub 2023 Feb 17.
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Quality of life in sinonasal tumors: an up-to-date review.鼻窦肿瘤患者的生活质量:最新综述。
Curr Opin Otolaryngol Head Neck Surg. 2022 Feb 1;30(1):46-57. doi: 10.1097/MOO.0000000000000774.
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Morbidity and Volumetric Progression in Juvenile Nasopharyngeal Angiofibroma in a Long-Term Follow-Up.
青少年鼻咽血管纤维瘤长期随访中的发病率及体积进展情况
J Neurol Surg B Skull Base. 2018 Dec;79(6):533-537. doi: 10.1055/s-0038-1635255. Epub 2018 Apr 9.
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Preoperative embolization of skull base meningiomas: current indications, techniques, and pearls for complication avoidance.颅底脑膜瘤的术前栓塞:当前的适应证、技术和避免并发症的要点。
Neurosurg Focus. 2018 Apr;44(4):E5. doi: 10.3171/2018.1.FOCUS17686.
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Patterns of vascularization and surgical morbidity in juvenile nasopharyngeal angiofibroma: A case series, systematic review, and meta-analysis.青少年鼻咽血管纤维瘤的血管形成模式与手术并发症:病例系列、系统评价和荟萃分析
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Microspheres embolization of juvenile nasopharyngeal angiofibroma in an adult.成人青少年鼻咽血管纤维瘤的微球栓塞术
Int J Surg Case Rep. 2014;5(12):1203-6. doi: 10.1016/j.ijscr.2014.10.019. Epub 2014 Nov 18.
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A comparison of particulate and onyx embolization in preoperative devascularization of juvenile nasopharyngeal angiofibromas.对比颗粒状和孔雀石栓塞在青少年鼻咽血管纤维瘤术前血管阻断中的作用。
Neuroradiology. 2013 Sep;55(9):1089-96. doi: 10.1007/s00234-013-1213-2. Epub 2013 Jun 9.
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