Wang Yunxia, Hu Wenting, Lin Fuquan, Xu Ai E
Department of Dermatology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, People's Republic of China.
Department of Dermatology, Hangzhou Third People's Hospital, Hangzhou, Zhejiang Province, People's Republic of China.
Clin Cosmet Investig Dermatol. 2023 Jul 25;16:1945-1948. doi: 10.2147/CCID.S420342. eCollection 2023.
Graft versus host disease (GVHD) is a complex immune-mediated pathophysiological process, which is caused by allogenic immune reactions between donors and recipients. No matter ac-ute or chronic GVHD, skin involvement is the most common, severe skin damage can lead to permanent disfigurement, which seriously affects the long-term quality of life of patients. We herein report a patient with generalized vitiligo after allogeneic peripheral hematopoietic stem cell transplantation (allo-HSCT) for aplastic anemia.
移植物抗宿主病（GVHD）是一个复杂的免疫介导的病理生理过程，由供体和受体之间的同种异体免疫反应引起。无论急性还是慢性GVHD，皮肤受累最为常见，严重的皮肤损伤可导致永久性毁容，严重影响患者的长期生活质量。我们在此报告一例再生障碍性贫血患者在接受异基因外周造血干细胞移植（allo-HSCT）后发生泛发性白癜风。
