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保留子宫的子宫动脉栓塞术治疗产后出血后子宫坏死的管理

Hysterectomy Sparing Management of Uterine Necrosis following Uterine Artery Embolization for Postpartum Hemorrhage.

作者信息

Chlela Myriam, Dawkins Josette, Lewis Gregory

机构信息

Department of Obstetrics and Gynecology, United Health Services Perinatal Center, 33-57 Harrison Street, Johnson City, NY 13790, USA.

Department of Obstetrics and Gynecology, Baystate Medical Center, 759 Chestnut Street, Springfield, MA 01199, USA.

出版信息

Case Rep Obstet Gynecol. 2023 Jul 19;2023:8276110. doi: 10.1155/2023/8276110. eCollection 2023.

Abstract

BACKGROUND

Postpartum hemorrhage (PPH) is one of the leading causes of maternal morbidity and mortality. Uterine artery embolization (UAE) is an effective procedural intervention for controlling PPH. Uterine necrosis (UN) is a rare complication of UAE and its management usually results in hysterectomy. We highlight a case of UAE complicated by UN managed conservatively without hysterectomy.

CASE

This is the case of a 30-year-old patient who had a cesarean section delivery and subsequently developed PPH due to uterine atony. The estimated blood loss (EBL) was 2500 ml; despite the use of uterotonic medications and trial of intrauterine balloon tamponade. She successfully underwent a UAE with no immediate complications. The remainder of her postnatal course was uncomplicated, and she was discharged on postoperative day 4. On postoperative day 28, the patient presented with fever, vaginal discharge, and abdominal pain. An abdomino-pelvic computed tomography scan revealed areas of necrosis within the uterus secondary to recent UAE. After minimal clinical improvement, the patient underwent a dilation and curettage with ultrasound guidance. The patient improved clinically and was discharged home to complete a 14-day course of antibiotics.

CONCLUSION

UAE is an important minimally invasive approach to the management of PPH. UN following UAE can present a clinical challenge to physicians, with the underlying pathophysiology being use of small embolizing particles during UAE and lack of arterial collaterals to embolized areas. A total of 19 cases of UN post-UAE have been described of which most of these cases were managed with a hysterectomy. In this case, an alternative treatment plan was successfully implemented via dilation and curettage under ultrasound guidance for removal of organized necrotic tissue. This was sufficient to improve the patient's symptoms and clinical outcome and saved the patient from the morbidity and mortality risks associated with a hysterectomy.

摘要

背景

产后出血(PPH)是孕产妇发病和死亡的主要原因之一。子宫动脉栓塞术(UAE)是控制PPH的一种有效手术干预措施。子宫坏死(UN)是UAE的一种罕见并发症,其治疗通常导致子宫切除术。我们重点介绍一例UAE并发UN且未行子宫切除术而保守治疗的病例。

病例

这是一名30岁患者的病例,她接受了剖宫产分娩,随后因子宫收缩乏力而发生PPH。估计失血量(EBL)为2500毫升;尽管使用了宫缩剂并尝试了宫腔球囊填塞。她成功接受了UAE,没有立即出现并发症。她产后的其余过程无并发症,术后第4天出院。术后第28天,患者出现发热、阴道分泌物增多和腹痛。腹部盆腔计算机断层扫描显示,继发于近期UAE的子宫内有坏死区域。在临床症状稍有改善后,患者在超声引导下进行了刮宫术。患者临床症状改善,出院回家完成14天的抗生素疗程。

结论

UAE是治疗PPH的一种重要的微创方法。UAE后的UN可能给医生带来临床挑战,其潜在病理生理机制是UAE期间使用了小的栓塞颗粒以及栓塞区域缺乏动脉侧支。总共已描述了19例UAE后发生UN的病例,其中大多数病例采用子宫切除术治疗。在本病例中,通过超声引导下刮宫术成功实施了替代治疗方案,以清除机化的坏死组织。这足以改善患者的症状和临床结局,并使患者免于子宫切除术相关的发病和死亡风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/158a/10372334/4793a249068e/CRIOG2023-8276110.001.jpg

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