Zhang Zhiming, Yang Qing
Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.
Front Med (Lausanne). 2023 Jul 13;10:1234861. doi: 10.3389/fmed.2023.1234861. eCollection 2023.
Primary diffuse large B-cell tumor of the uterus is a rare clinical condition with a similar clinical presentation to gynecologic tumors and is easily misdiagnosed. We report a case of a postmenopausal woman who presented with pelvic mass. Her ultrasound and MRI examinations suggested diffuse enlargement of the uterus, leading us to consider the diagnosis of lymphoma. The histological examination of the uterine mass confirmed the diagnosis of diffuse large B-cell lymphoma. The patient received 6 cycles of chemotherapy with R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone) and 2 cycles of consolidation therapy with R (rituximab). After treatment, the patient's uterus was significantly smaller than before and there was no sign of a recurrence.
原发性子宫弥漫性大B细胞肿瘤是一种临床罕见疾病，临床表现与妇科肿瘤相似，容易误诊。我们报告一例绝经后女性患者，该患者因盆腔肿块就诊。她的超声和磁共振成像检查提示子宫弥漫性增大，使我们考虑淋巴瘤的诊断。子宫肿块的组织学检查确诊为弥漫性大B细胞淋巴瘤。患者接受了6个周期的R-CHOP（利妥昔单抗、环磷酰胺、多柔比星、长春新碱和泼尼松）化疗以及2个周期的R（利妥昔单抗）巩固治疗。治疗后，患者的子宫明显比之前缩小，且无复发迹象。
