Tsunoda Tomoaki, Yasuda Tomohiro, Igaki Ryu, Takagi Shinsuke, Kawasaki Keikichi, Kanzaki Koji
Department of Orthopaedic Surgery, Showa University Fujigaoka Hospital, Yokohama, Japan.
Department of Plastic and Reconstructive Surg, Showa University School of Medicine, Tokyo, Japan.
J Orthop Case Rep. 2023 Jul;13(7):41-46. doi: 10.13107/jocr.2023.v13.i07.3746.
Post-traumatic osteomyelitis (OM) is often caused by Staphylococcus aureus. However, occasionally, it is caused by an infection with a rare bacterium. A case of OM caused by Aeromonas hydrophila was first reported in 1975. Since then, only nine cases have been reported, making it a rare disease. Here, we report a case of rare A. hydrophila OM that developed following open tibial fracture (classified as Gustilo-Anderson 3B) caused by an injury in a river.
The patient was a 50-year-old male who got injured in a river and was diagnosed with open tibial fracture. Debridement in the first surgery happened at a leisurely pace. Purulent discharge from the wound persisted despite external fixation; however, no bacterium was detected in the bacterial culture. The patient underwent multiple debridement procedures; A. hydrophila was detected in the bone marrow. Despite the appropriate administration of antibacterial drugs and debridement, infection persisted until radical bone resection and tissue reconstruction were performed. In the present case, OM following an open fracture caused by an injury in a river was suspected, which was caused by the rare bacterium A. hydrophila.
In cases of OM occurring after underwater trauma, A. hydrophila should be considered as a causative pathogen. In addition, in cases of post-traumatic OM accompanied by bone and soft-tissue defects, the orthoplastic approach is required.
创伤后骨髓炎(OM)通常由金黄色葡萄球菌引起。然而,偶尔也由罕见细菌感染所致。1975年首次报道了1例由嗜水气单胞菌引起的OM病例。自那时以来,仅报告了9例,使其成为一种罕见疾病。在此,我们报告1例罕见的嗜水气单胞菌所致OM病例,该病例发生于因河中受伤导致的开放性胫骨骨折(分类为 Gustilo-Anderson 3B型)之后。
患者为一名50岁男性,在河中受伤,被诊断为开放性胫骨骨折。首次手术清创过程较为缓慢。尽管进行了外固定,伤口仍持续有脓性分泌物;然而,细菌培养未检测到细菌。患者接受了多次清创手术;在骨髓中检测到嗜水气单胞菌。尽管适当使用了抗菌药物并进行了清创,但感染持续存在,直至进行了根治性骨切除和组织重建。在本病例中,怀疑河中受伤导致的开放性骨折后发生的OM是由罕见细菌嗜水气单胞菌引起的。
在水下创伤后发生OM的病例中,应考虑嗜水气单胞菌为致病病原体。此外,在伴有骨和软组织缺损的创伤后OM病例中,需要采用骨整形方法。