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乳腺淋巴上皮癌

Lymphoepithelial Carcinoma of the Breast.

作者信息

Arora Mamta, Balasubramanian Balaji, Mohammad Kamel Aljasem Naemieh, Arora Simran, Arora Ravi

机构信息

Department of Surgery, NMC Specialty Hospital, Abu Dhabi, Abu Dhabi, ARE.

Department of Surgery and Oncology, NMC Specialty Hospital, Abu Dhabi, Abu Dhabi, ARE.

出版信息

Cureus. 2023 Jul 28;15(7):e42597. doi: 10.7759/cureus.42597. eCollection 2023 Jul.

Abstract

Lymphoepithelial malignancy is an extremely rare carcinoma of the breast characterized by a confusing histopathological picture resembling medullary carcinomas, lymphoma, etc. It has also been reported in other regions of the body like salivary glands, nasopharyngeal area and sometimes the lung. Due to its rare presence and difficult diagnosis, the treatment is often prolonged and delayed. Here we present a case report of a 56-year-old lady who was eventually diagnosed as lymphoepithelial carcinoma of the breast. Her journey of evaluation and treatment was fraught with pathological nuances and an elimination drill of multiple differentials before concluding this rare diagnosis. Although lymphoepithelial-like carcinoma is a rare entity, multiple cases have been reported in the literature and their review is mandated to further our clinical knowledge about the oncological treatment and expected prognosis of such cases in the future. Our patient underwent a simple mastectomy, followed by chemotherapy, radiotherapy, and is completely asymptomatic now. She has been cancer-free for the last seven years so far.

摘要

淋巴上皮恶性肿瘤是一种极为罕见的乳腺癌,其组织病理学表现令人困惑,类似于髓样癌、淋巴瘤等。它也在身体的其他部位被报道过,如唾液腺、鼻咽部,有时也见于肺部。由于其罕见性和诊断困难,治疗往往会延长且延迟。在此,我们报告一例56岁女性病例,最终被诊断为乳腺淋巴上皮癌。她的评估和治疗过程充满了病理细微差别以及在得出这一罕见诊断之前对多种不同诊断的排除过程。尽管淋巴上皮样癌是一种罕见的实体,但文献中已报道了多例病例,对其进行综述有助于我们进一步了解此类病例未来的肿瘤治疗及预期预后的临床知识。我们的患者接受了单纯乳房切除术,随后进行了化疗、放疗,目前完全无症状。到目前为止,她在过去七年中一直无癌生存。

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