Goldstein M B, Bear R, Richardson R M, Marsden P A, Halperin M L
Am J Med Sci. 1986 Oct;292(4):198-202. doi: 10.1097/00000441-198610000-00003.
In patients with a normal plasma anion gap type of metabolic acidosis, knowledge of the rate of ammonium excretion can provide valuable information to determine if there is a renal cause for the disorder. Unfortunately, few hospital biochemistry laboratories offer routine determination of the urine ammonium concentration. Data are presented that demonstrate a direct linear relationship between the urine anion gap (Na+ + K+ - Cl-) and the urine ammonium concentration. In a 24-hour urine collection, the relationship is urine ammonium equals -0.8 (urine anion gap) +82 (r = 0.97 p less than 0.01). The applications of this index of ammonium excretion are discussed.
在患有正常血浆阴离子间隙型代谢性酸中毒的患者中，了解铵排泄率可为确定该病症是否存在肾脏病因提供有价值的信息。遗憾的是，很少有医院生化实验室提供尿铵浓度的常规测定。所呈现的数据表明尿阴离子间隙（Na⁺ + K⁺ - Cl⁻）与尿铵浓度之间存在直接线性关系。在24小时尿液收集过程中，这种关系为尿铵等于 -0.8（尿阴离子间隙）+82（r = 0.97，p小于0.01）。本文讨论了这种铵排泄指标的应用。
