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高压氧疗法治疗假单胞菌性眼内炎和眼眶蜂窝织炎患者的组织坏死:一例报告

Treatment of tissue necrosis with hyperbaric oxygen therapy in a patient with pseudomonas endophthalmitis and orbital cellulitis: a case report.

作者信息

Uyanik Ismail, Topcu Husna, Cabuk Kubra Serefoglu, Efe Ayse Cetin, Ulas Mehmet Goksel

机构信息

University of Health Sciences, Istanbul, Turkey; Beyoglu Eye Training and Research Hospital, Istanbul, Turkey.

出版信息

Rom J Ophthalmol. 2023 Apr-Jun;67(2):191-194. doi: 10.22336/rjo.2023.33.

DOI:10.22336/rjo.2023.33
PMID:37522028
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10385712/
Abstract

This report presents the treatment of tissue necrosis after evisceration with hyperbaric oxygen therapy (HBOT) in a patient with pseudomonas endophthalmitis and orbital cellulitis. A 49-year-old woman was admitted to our clinic with severe pain and vision loss after cataract surgery 3 days before, and pars plana vitrectomy 2 days before for endophthalmitis, in another hospital. Examination findings included limbal perforation, orbital cellulitis findings, and loss of light perception in the right eye. The patient, who received evisceration surgery and antibiotic treatment, showed loosening of the conjunctival sutures and necrosis in the conjunctiva, tenon, and sclera on the 9th postoperative day. The necrotic tissues were surgically debrided and the patient was referred to HBOT. With HBOT and antibiotherapy, signs of inflammation regressed, healing on the conjunctival surface was accelerated, and prosthesis was suitable for use. Hyperbaric oxygen therapy is a treatment method that plays an active role in the healing of necrotic tissues by increasing the oxygenation and vascularization of the tissue.

摘要

本报告介绍了高压氧疗法(HBOT)治疗一名患有假单胞菌性眼内炎和眼眶蜂窝织炎患者眼球摘除术后组织坏死的情况。一名49岁女性在3天前白内障手术后出现严重疼痛和视力丧失,2天前在另一家医院因眼内炎接受了玻璃体切割术,随后入住我院。检查结果包括角膜缘穿孔、眼眶蜂窝织炎表现以及右眼光感丧失。该患者接受了眼球摘除手术和抗生素治疗,术后第9天出现结膜缝线松动以及结膜、眼球筋膜和巩膜坏死。对坏死组织进行了手术清创,随后患者接受了高压氧疗法。通过高压氧疗法和抗生素治疗,炎症体征消退,结膜表面愈合加速,义眼台适合使用。高压氧疗法是一种通过增加组织的氧合作用和血管形成,在坏死组织愈合中发挥积极作用的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a834/10385712/80c57b187799/RomJOphthalmol-67-191-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a834/10385712/75566f6f3808/RomJOphthalmol-67-191-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a834/10385712/91a2c98d2159/RomJOphthalmol-67-191-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a834/10385712/f32b4a8c5aba/RomJOphthalmol-67-191-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a834/10385712/80c57b187799/RomJOphthalmol-67-191-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a834/10385712/75566f6f3808/RomJOphthalmol-67-191-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a834/10385712/91a2c98d2159/RomJOphthalmol-67-191-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a834/10385712/f32b4a8c5aba/RomJOphthalmol-67-191-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a834/10385712/80c57b187799/RomJOphthalmol-67-191-g004.jpg

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Pathogens. 2021 Jul 7;10(7):854. doi: 10.3390/pathogens10070854.
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Orbital cellulitis as complication of endophthalmitis after cataract surgery.眼球蜂窝织炎作为白内障手术后眼内炎的并发症。
J Cataract Refract Surg. 2010 Apr;36(4):673-5. doi: 10.1016/j.jcrs.2009.08.044.
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