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硫丹最大残留限量(MRLs)的针对性审查。

Targeted review of maximum residue levels (MRLs) for endosulfan.

作者信息

Bellisai Giulia, Bernasconi Giovanni, Binaglia Marco, Carrasco Cabrera Luis, Castellan Irene, Castoldi Anna Federica, Chiusolo Arianna, Crivellente Federica, Del Aguila Monica, Ferreira Lucien, Santonja German Giner, Greco Luna, Istace Frederique, Jarrah Samira, Lanzoni Anna, Leuschner Renata, Mangas Iris, Miron Ileana, Nave Stefanie, Panzarea Martina, Parra Morte Juan Manuel, Pedersen Ragnor, Reich Hermine, Ruocco Silvia, Santos Miguel, Scarlato Alessia Pia, Terron Andrea, Theobald Anne, Tiramani Manuela, Verani Alessia

出版信息

EFSA J. 2023 Jul 27;21(7):e08114. doi: 10.2903/j.efsa.2023.8114. eCollection 2023 Jul.

DOI:10.2903/j.efsa.2023.8114
PMID:37522102
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10373131/
Abstract

In accordance with Article 43 of Regulation (EC) 396/2005, EFSA received a request from the European Commission to review the existing maximum residue levels (MRLs) for the non-approved active substance endosulfan in view of the possible lowering of the MRLs. EFSA investigated the origin of the current EU MRLs. For existing EU MRLs that reflect previously authorised uses in the EU, or that are based on obsolete Codex maximum residue limits, or import tolerances that are not required any longer, EFSA proposed the lowering to the limit of quantification or to an alternative MRL. EFSA performed an indicative chronic and acute dietary risk assessment for the revised list of MRLs to allow risk managers to take the appropriate decisions. For all commodities, further risk management discussions are required to decide which of the risk management options proposed by EFSA should be implemented in the EU MRL legislation.

摘要

根据欧盟法规(EC)396/2005第43条,欧洲食品安全局(EFSA)收到欧盟委员会的请求,鉴于可能降低硫丹这一未批准活性物质的最大残留限量(MRLs),对其现有最大残留限量进行审查。EFSA调查了当前欧盟最大残留限量的来源。对于反映欧盟先前授权使用情况、基于过时的食品法典最大残留限量或不再需要的进口容忍度的现有欧盟最大残留限量,EFSA提议将其降低至定量限或替代最大残留限量。EFSA对修订后的最大残留限量清单进行了指示性慢性和急性膳食风险评估,以便风险管理者做出适当决策。对于所有商品,需要进一步进行风险管理讨论,以决定应在欧盟最大残留限量法规中实施EFSA提议的哪些风险管理选项。

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本文引用的文献

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Scientific support for preparing an EU position in the 55th Session of the Codex Committee on Pesticide Residues (CCPR).为在农药残留法典委员会(CCPR)第55届会议上制定欧盟立场提供科学支持。
EFSA J. 2024 Jul 18;22(7):e8841. doi: 10.2903/j.efsa.2024.8841. eCollection 2024 Jul.
2
Guidance for the identification of endocrine disruptors in the context of Regulations (EU) No 528/2012 and (EC) No 1107/2009.关于在(欧盟)第528/2012号法规和(欧盟)第1107/2009号法规背景下识别内分泌干扰物的指南。
EFSA J. 2018 Jun 7;16(6):e05311. doi: 10.2903/j.efsa.2018.5311. eCollection 2018 Jun.
3
Use of EFSA Pesticide Residue Intake Model (EFSA PRIMo revision 3).使用欧洲食品安全局农药残留摄入模型(EFSA PRIMo第3版修订本)。
EFSA J. 2018 Jan 15;16(1):e05147. doi: 10.2903/j.efsa.2018.5147. eCollection 2018 Jan.
4
Human health risk assessment of endosulfan. I: Toxicology and hazard identification.内硫丹对人类健康的风险评估。I:毒理学和危害识别。
Regul Toxicol Pharmacol. 2010 Feb;56(1):4-17. doi: 10.1016/j.yrtph.2009.08.013. Epub 2009 Sep 3.