Center for Infectious Diseases, West China Hospital, Sichuan University, Chengdu, 610044, PR China.
Department of Infectious Disease, People's Hospital of Aba Tibetan & Qiang Autonomous Prefecture, Aba State, 624099, PR China.
Future Microbiol. 2023 Jul;18:699-705. doi: 10.2217/fmb-2023-0038. Epub 2023 Jul 31.
Visceral leishmaniasis (VL) is a parasitic disease caused by spp., which is transmitted by sandflies. As China is not the main epidemic area and VL has complex and atypical clinical manifestations, it is easily misdiagnosed or even missed in clinical practice. Without prompt and efficient treatment, the mortality rate of VL is extremely high; therefore early diagnosis of VL is crucial. Herein we describe a case of fever and splenomegaly of unknown origin, which was finally diagnosed as VL by metagenomic next-generation sequencing.
内脏利什曼病（VL）是一种由 spp.引起的寄生虫病，通过沙蝇传播。由于中国并非主要流行区，且 VL 的临床表现复杂且不典型，因此在临床实践中极易误诊甚至漏诊。如果未能及时有效地治疗，VL 的死亡率极高；因此，早期诊断 VL 至关重要。本文报道了 1 例发热伴脾大的不明原因患者，最终通过宏基因组二代测序诊断为 VL。
