Department of Anesthesiology, Cangzhou People's Hospital, Cangzhou, China.
Eur Rev Med Pharmacol Sci. 2023 Jul;27(14):6510-6522. doi: 10.26355/eurrev_202307_33121.
In this work, based on intelligent computing, the biological signals of patients were analyzed to investigate the hemodynamic changes and pulmonary complications of Nalmefene Hcl combined with general anesthesia (GA) in laparoscopic gynecological tumor surgery (GTS).
Eighty computer-aided GTS patients were randomly divided into a control group (n = 40) and an observation group (n = 40). Biomedical electrocardiogram (ECG) signals were detected by wavelet neural network in all patients undergoing laparoscopic gynecological tumor surgery and were computerized according to the android interface definition language model (AIDL). GA was used during surgery. The observation group was injected intravenously with 0.2 μg/kg naproxenacin hydrochloride after operation. The control group was given 1 mL 0.9% sodium chloride solution after operation. Mean arterial pressure (MAP), heart rate (HR), respiratory rate (RR), pulse oxygen saturation (SPO), coma score, and adverse reactions (AR) were compared between the two groups at 10, 20, and 30 minutes after wakefulness. The hemodynamic parameters between the two groups were compared. Serum urocholine (URO) and creatinine (Cre) levels were analyzed in patients without complications.
ECG waveform based on wavelet neural network has a high recognition rate and strong generalization ability. 37 patients in the observation group recovered within 10 minutes after surgery, and the recovery rate at 30 minutes was 95%. 30 patients in the control group awoke 10 minutes after the operation, and the recovery rate at 30 minutes m-AR was 75%. The average abstract windows toolkit (AWT) of the observation group and control group was 11.87 ± 5.78 min and 16.46 ± 5.32 min, respectively, and the difference was significant (p < 0.05). There were significant differences in HR, systolic blood pressure (SBP), and diastolic blood pressure (DBP) between the observation group and the control group during the extubation (p < 0.05). Blood gas indexes PaO2, PvO2, PaCO2, and PvCO2 in the observation group were significantly different from those in the control group half an hour after the operation and half an hour after pneumoperitoneum (p > 0.05).
Intelligent computational biological signal detection was beneficial to the development of surgery. Nalmefene Hcl combined with GA on the basis of the AIDL model has a significant effect on the awakening of GTS patients and can shorten sleep time. Patients with underlying cardiac disease were more likely to develop postoperative lung complications.
本研究基于智能计算,分析患者的生物信号,探讨盐酸纳美芬联合全身麻醉(GA)在腹腔镜妇科肿瘤手术(GTS)中血流动力学变化和肺部并发症的关系。
将 80 例计算机辅助 GTS 患者随机分为对照组(n=40)和观察组(n=40)。所有患者在接受腹腔镜妇科肿瘤手术后均采用小波神经网络检测生物医学心电图(ECG)信号,并根据安卓接口定义语言模型(AIDL)进行计算机化。术中采用 GA。观察组术后静脉注射 0.2μg/kg 盐酸纳美芬,对照组术后给予 1mL0.9%氯化钠溶液。两组患者在清醒后 10、20、30min 时比较平均动脉压(MAP)、心率(HR)、呼吸频率(RR)、脉搏血氧饱和度(SPO)、昏迷评分和不良反应(AR),比较两组患者的血流动力学参数。分析无并发症患者的血清尿胆素(URO)和肌酐(Cre)水平。
基于小波神经网络的 ECG 波形具有较高的识别率和较强的泛化能力。观察组 37 例患者术后 10min 内恢复,30min 恢复率为 95%;对照组 30 例患者术后 10min 清醒,30min 时 m-AR 恢复率为 75%。观察组和对照组的平均抽象窗口工具包(AWT)分别为 11.87±5.78min 和 16.46±5.32min,差异有统计学意义(p<0.05)。观察组和对照组在拔管时 HR、收缩压(SBP)和舒张压(DBP)差异有统计学意义(p<0.05)。观察组患者血气指标 PaO2、PvO2、PaCO2 和 PvCO2 在术后半小时和半气腹后半小时与对照组相比差异有统计学意义(p>0.05)。
智能计算生物信号检测有利于手术的发展。基于 AIDL 模型的盐酸纳美芬联合 GA 对 GTS 患者的觉醒有显著效果,可缩短睡眠时间。合并基础心脏疾病的患者更容易发生术后肺部并发症。