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全国范围内关于乙状结肠憩室炎手术住院死亡率和救援失败的量效关系。

Nationwide volume-outcome relationship concerning in-hospital mortality and failure-to-rescue in surgery of sigmoid diverticulitis.

机构信息

Department of General, Visceral, Transplant, Vascular and Pediatric Surgery at, Würzburg University Hospital, Würzburg, Germany.

Department of Thoracic Surgery, Thoraxklinik at Heidelberg University Hospital, Heidelberg, Germany.

出版信息

Int J Colorectal Dis. 2023 Jul 31;38(1):203. doi: 10.1007/s00384-023-04495-6.

DOI:10.1007/s00384-023-04495-6
PMID:37522984
Abstract

PURPOSE

A correlation between the hospital volume and outcome is described for multiple entities of oncological surgery. To date, this has not been analyzed for the surgical treatment of sigmoid diverticulitis. The aim of this study was to explore the impact of the annual caseload per hospital of colon resection on the postoperative incidence of complications, failure to rescue, and mortality in patients with diverticulitis.

METHODS

Patients receiving colorectal resection independent from the diagnosis from 2012 to 2017 were selected from a German nationwide administrative dataset. The hospitals were grouped into five equal caseload quintiles (Q1-Q5 in ascending caseload order). The outcome analysis was focused on patients receiving surgery for sigmoid diverticulitis.

RESULTS

In total, 662,706 left-sided colon resections were recorded between 2012 and 2017. Of these, 156,462 resections were performed due to sigmoid diverticulitis and were included in the analysis. The overall in-house mortality rate was 3.5%, ranging from 3.8% in Q1 (mean of 9.5 procedures per year) to 3.1% in Q5 (mean 62.8 procedures per year; p < 0.001). Q5 hospitals revealed a risk-adjusted odds ratio of 0.85 (95% CI 0.78-0.94; p < 0.001) for in-hospital mortality compared to Q1 during multivariable logistic regression analysis. High-volume centers showed overall lower complication rates, whereas the failure-to-rescue did not differ significantly.

CONCLUSION

Surgical treatment of sigmoid diverticulitis in high-volume colorectal centers shows lower postoperative mortality rates and fewer postoperative complications.

摘要

目的

描述了多种肿瘤外科手术与医院容量之间的相关性。迄今为止,对于乙状结肠憩室炎的手术治疗,尚未对此进行分析。本研究旨在探讨医院每年每例结肠切除术的病例数对憩室炎患者术后并发症、抢救失败和死亡率的影响。

方法

从德国国家行政数据集选择 2012 年至 2017 年接受与诊断无关的结直肠切除术的患者。将医院分为五组,每组病例数相等(按病例数升序排列为 Q1-Q5)。结果分析侧重于因乙状结肠憩室炎而行手术的患者。

结果

2012 年至 2017 年期间共记录了 662706 例左侧结肠切除术。其中,156462 例因乙状结肠憩室炎而行切除术,并纳入分析。总体院内死亡率为 3.5%,范围从 Q1 的 3.8%(每年平均 9.5 例)到 Q5 的 3.1%(每年平均 62.8 例;p<0.001)。多变量逻辑回归分析显示,与 Q1 相比,Q5 医院的风险调整比值比为 0.85(95%CI 0.78-0.94;p<0.001)。高容量中心总体显示出较低的并发症发生率,而抢救失败没有显著差异。

结论

在高容量结直肠中心进行乙状结肠憩室炎的手术治疗显示出较低的术后死亡率和较少的术后并发症。

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本文引用的文献

1
Hospital volume following major surgery for gastric cancer determines in-hospital mortality rate and failure to rescue: a nation-wide study based on German billing data (2009-2017).基于德国计费数据的全国性研究(2009-2017 年):胃癌大手术后的医院容量决定住院死亡率和抢救失败率。
Gastric Cancer. 2021 Jul;24(4):959-969. doi: 10.1007/s10120-021-01167-8. Epub 2021 Feb 12.
2
The Indications for and Timing of Surgery for Diverticular Disease.憩室病的手术适应证和时机。
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Mortality and complication management after surgery for colorectal cancer depending on the DKG minimum amounts for hospital volume.
新冠疫情期间德国憩室炎患者的护理:一项回顾性全国基于人群的队列研究。
Langenbecks Arch Surg. 2023 Nov 25;408(1):447. doi: 10.1007/s00423-023-03184-w.
结直肠癌手术后的死亡率和并发症管理取决于医院量的 DKG 最低量。
Eur J Surg Oncol. 2021 Apr;47(4):850-857. doi: 10.1016/j.ejso.2020.09.024. Epub 2020 Sep 25.
4
Nationwide effect of high procedure volume in lung cancer surgery on in-house mortality in Germany.德国肺癌手术高手术量对院内死亡率的全国性影响。
Lung Cancer. 2020 Nov;149:78-83. doi: 10.1016/j.lungcan.2020.08.018. Epub 2020 Aug 31.
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In-hospital mortality and failure to rescue following hepatobiliary surgery in Germany - a nationwide analysis.德国肝胆手术后的院内死亡率及抢救失败情况——一项全国性分析
BMC Surg. 2020 Jul 29;20(1):171. doi: 10.1186/s12893-020-00817-5.
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Nationwide in-hospital mortality rate following rectal resection for rectal cancer according to annual hospital volume in Germany.德国根据年度医院手术量统计的直肠癌直肠切除术后全国住院死亡率。
BJS Open. 2020 Apr;4(2):310-319. doi: 10.1002/bjs5.50254. Epub 2020 Jan 10.
7
Mortality and Complications Following Visceral Surgery: A Nationwide Analysis Based on the Diagnostic Categories Used in German Hospital Invoicing Data.内脏手术后的死亡率和并发症:基于德国医院计费数据中使用的诊断类别进行的全国性分析。
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Int J Colorectal Dis. 2018 Mar;33(3):261-272. doi: 10.1007/s00384-017-2960-z. Epub 2018 Jan 18.