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金融脆弱性及其与吉尔吉斯斯坦注射吸毒者中 HIV 传播风险行为的关联。

Financial Vulnerability and Its Association with HIV Transmission Risk Behaviors Among People Who Inject Drugs in Kyrgyzstan.

机构信息

Center for Health Promotion and Disease Prevention, Edson College of Nursing and Health Innovation, Arizona State University, Phoenix, AZ, USA.

Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California, San Diego, La Jolla, CA, 92093-0507, USA.

出版信息

AIDS Behav. 2024 Jan;28(1):310-319. doi: 10.1007/s10461-023-04129-6. Epub 2023 Jul 31.

DOI:10.1007/s10461-023-04129-6
PMID:37523049
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11376237/
Abstract

The Family Resource Scale (FRS) is a three-factor financial vulnerability (FV) measure. FV may impact HIV transmission risks. Cross-sectional data from 279 people who inject drugs (PWID) in Kyrgyzstan surveyed April-October 2021 was used to validate the FRS and estimate associations between FV on past 6-month injection and sexual HIV risk outcomes. The three-factor FRS reflected housing, essential needs, and fiscal independence, and had good internal reliability and structural validity. Greater cumulative, housing, and essential needs FRS scores were associated with increased relative risk on public injection (adjusted risk ratio [aRR], 95% confidence interval [95% CI]: 1.03 [1.01, 1.04]; aRR [95% CI]: 1.06 [1.02, 1.09]; aRR [95% CI]: 1.06 [1.03, 1.08], respectively, all p < 0.001) and preparing injections with unsafe water sources (aRR [95% CI]: 1.04 [1.02, 1.07]; aRR [95% CI]: 1.09 [1.04, 1.15]; aRR [95% CI]: 1.08 [1.03, 1.14], respectively, all p < 0.001). Results suggest that PWID housing- and essential needs-related FV may exacerbate injection HIV transmission risks. Reducing PWIDs' FV may enhance the HIV response in Kyrgyzstan.

摘要

家庭资源量表（FRS）是一种三因素财务脆弱性（FV）衡量标准。FV 可能会影响 HIV 传播风险。本研究使用了 2021 年 4 月至 10 月在吉尔吉斯斯坦对 279 名注射吸毒者（PWID）进行的横断面数据来验证 FRS，并评估 FV 对过去 6 个月内注射和性行为 HIV 风险结果的关联。三因素 FRS 反映了住房、基本需求和财政独立，具有良好的内部可靠性和结构有效性。累积 FRS 评分、住房 FRS 评分和基本需求 FRS 评分越高，公共注射的相对风险增加（调整后的风险比 [aRR]，95%置信区间 [95%CI]：1.03 [1.01, 1.04]；aRR [95%CI]：1.06 [1.02, 1.09]；aRR [95%CI]：1.06 [1.03, 1.08]，均 p < 0.001），以及使用不安全水源准备注射的风险也增加（aRR [95%CI]：1.04 [1.02, 1.07]；aRR [95%CI]：1.09 [1.04, 1.15]；aRR [95%CI]：1.08 [1.03, 1.14]，均 p < 0.001）。结果表明，PWID 住房和基本需求相关的 FV 可能会加剧注射 HIV 传播风险。降低 PWID 的 FV 可能会增强吉尔吉斯斯坦的 HIV 应对能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b904/11376237/b5456c74f4db/nihms-2016471-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b904/11376237/b5456c74f4db/nihms-2016471-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b904/11376237/b5456c74f4db/nihms-2016471-f0001.jpg

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Factors associated with injecting-related risk behaviors among people who inject drugs: a systematic review and meta-analysis study.与注射吸毒者相关的注射相关风险行为的关联因素：系统评价和荟萃分析研究。
J Addict Dis. 2020 Oct-Dec;38(4):420-437. doi: 10.1080/10550887.2020.1781346. Epub 2020 Jul 7.
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Navigating environmental constraints to injection preparation: the use of saliva and other alternatives to sterile water among unstably housed PWID in London.
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Variable selection strategies and its importance in clinical prediction modelling.变量选择策略及其在临床预测模型中的重要性。
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