Qin Mengting, Chen Jiaojiao, Guo Xiaoqing, Xiang Xuying, Nie Lei, Wang Yong, Mao Ling
Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
J Neurol. 2023 Nov;270(11):5288-5302. doi: 10.1007/s00415-023-11881-1. Epub 2023 Jul 31.
Autoimmune encephalitis (AE) is a form of encephalitis resulting from an immune response targeting central nervous system antigens, which is characterized by cognitive impairment, neuropsychiatric symptoms, seizures, movement disorders (MDs), and other encephalopathy symptoms. MDs frequently manifest throughout the progression of the disease, with recurrent involuntary movements leading to discomfort and, in some cases, necessitating admission to the intensive care unit. Prompt identification and management of MDs can aid in the diagnosis and prognosis of AE. This review synthesizes current knowledge on the characteristics, underlying mechanisms, and treatment options for MDs in the context of AE.
自身免疫性脑炎（AE）是一种由针对中枢神经系统抗原的免疫反应引起的脑炎，其特征为认知障碍、神经精神症状、癫痫发作、运动障碍（MDs）及其他脑病症状。运动障碍在疾病进展过程中经常出现，反复的不自主运动导致不适，在某些情况下需要入住重症监护病房。及时识别和处理运动障碍有助于自身免疫性脑炎的诊断和预后。本综述综合了自身免疫性脑炎背景下运动障碍的特征、潜在机制和治疗选择的现有知识。
