Post-stimulus encoding of decision confidence in EEG: toward a brain-computer interface for decision making.

When making decisions, humans can evaluate how likely they are to be correct. If this subjective confidence could be reliably decoded from brain activity, it would be possible to build a brain-computer interface (BCI) that improves decision performance by automatically providing more information to the user if needed based on their confidence. But this possibility depends on whether confidence can be decoded right after stimulus presentation and before the response so that a corrective action can be taken in time. Although prior work has shown that decision confidence is represented in brain signals, it is unclear if the representation is stimulus-locked or response-locked, and whether stimulus-locked pre-response decoding is sufficiently accurate for enabling such a BCI.We investigate the neural correlates of confidence by collecting high-density electroencephalography (EEG) during a perceptual decision task with realistic stimuli. Importantly, we design our task to include a post-stimulus gap that prevents the confounding of stimulus-locked activity by response-locked activity and vice versa, and then compare with a task without this gap.We perform event-related potential and source-localization analyses. Our analyses suggest that the neural correlates of confidence are stimulus-locked, and that an absence of a post-stimulus gap could cause these correlates to incorrectly appear as response-locked. By preventing response-locked activity from confounding stimulus-locked activity, we then show that confidence can be reliably decoded from single-trial stimulus-locked pre-response EEG alone. We also identify a high-performance classification algorithm by comparing a battery of algorithms. Lastly, we design a simulated BCI framework to show that the EEG classification is accurate enough to build a BCI and that the decoded confidence could be used to improve decision making performance particularly when the task difficulty and cost of errors are high.Our results show feasibility of non-invasive EEG-based BCIs to improve human decision making.