脊柱裂患儿和非脊柱裂患儿的身高和体重指数分布。

Height and body mass index distribution in children and adolescents with and without spina bifida.

机构信息

Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Ciências da Saúde, Ribeirão Preto, SP, Brazil.

出版信息

J Pediatr (Rio J). 2024 Jan-Feb;100(1):46-52. doi: 10.1016/j.jped.2023.07.002. Epub 2023 Jul 29.

DOI:10.1016/j.jped.2023.07.002

PMID:37524313

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10751691/

Abstract

OBJECTIVE

Children with spina bifida (SB) are at risk for stunting and overweight. However, height and Body Mass Index (BMI) z-score distribution in children and adolescents with SB are unclear. The aim of this study was to examine height and BMI z-score distribution in Brazilian children and adolescents with and without SB. This study further aimed to examine whether height and BMI z-scores differ between individuals with and without SB.

METHOD

This study included 101 participants (SB: n = 18; non-SB: n = 83, aged 7-16 years). The World Health Organization (WHO) AnthroPlus software was used to calculate height and BMI z-scores. AnthroPlus z-score distribution graphs were used to examine individual z-scores based on the 2007 WHO normal distribution curve. Effects of the group (SB vs non-SB) on height and BMI z-scores were examined with sequential regression.

RESULTS

In the WHO distribution graph analysis, height z-scores of participants with SB were slightly left-shifted compared to the WHO normal distribution curve. In the regression analysis, group (SB vs non-SB) was a significant predictor of height z-scores after controlling for sex and age (ΔR = 0.064, p = 0.010). BMI z-scores of participants with SB were right-shifted compared to the WHO normal curve. However, there was no contribution of the group to BMI z-scores (ΔR = 0.011, p = 0.301).

CONCLUSIONS

These findings suggest that Brazilian children and adolescents with SB may be at risk for reduced height and increased BMI.

摘要

目的

患有脊柱裂（SB）的儿童存在发育迟缓与超重的风险。然而，患有 SB 的儿童和青少年的身高和体重指数（BMI）Z 评分分布情况尚不清楚。本研究旨在检验巴西患有和不患有 SB 的儿童和青少年的身高和 BMI Z 评分分布情况，并进一步检验是否患有 SB 会导致个体的身高和 BMI Z 评分存在差异。

方法

本研究纳入了 101 名参与者（SB：n=18；非 SB：n=83，年龄 7-16 岁）。采用世卫组织 AnthroPlus 软件计算身高和 BMI Z 评分。使用 AnthroPlus Z 评分分布图，根据 2007 年世卫组织的正常分布曲线，检验个体 Z 评分。采用逐步回归分析 SB 组与非 SB 组对身高和 BMI Z 评分的影响。

结果

在世卫组织分布图形分析中，与世卫组织正常分布曲线相比，患有 SB 的参与者的身高 Z 评分略有左移。在回归分析中，控制性别和年龄后，组间（SB 与非 SB）是身高 Z 评分的显著预测因子（ΔR=0.064，p=0.010）。与世卫组织正常曲线相比，患有 SB 的参与者的 BMI Z 评分右移。然而，组间对 BMI Z 评分没有贡献（ΔR=0.011，p=0.301）。