生物电阻抗分析在脊灰患儿体重管理中的应用。

Application of Bioelectrical Impedance Analysis in Weight Management of Children with Spina Bifida.

机构信息

Department of Pediatrics and Nephrology, Medical University of Białystok, 17 Waszyngton Str., 15-274 Białystok, Poland.

出版信息

Nutrients. 2024 Sep 23;16(18):3222. doi: 10.3390/nu16183222.

DOI:10.3390/nu16183222

PMID:39339822

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11435372/

Abstract

BACKGROUND

Children with spina bifida (SB) face an elevated risk of obesity, which necessitates precise methods for assessing body composition to ensure effective weight management. Conventional measures like BMI are inadequate for this population because of variations in growth patterns and skeletal structure. Bioelectrical impedance analysis (BIA) is a method that offers a clearer picture of body composition, yet its use in children with SB remains underexplored.

METHODS

Conducted on 57 children with SB and 28 healthy controls, with a median age of 11 years, this study evaluated anthropometrics, including BMI and BIA-derived metrics. The Hoffer's scale to assess physical activity was applied in SB children.

RESULTS

Results showed that while 32% of SB patients were classified as overweight or obese based on BMI, 62% exhibited high body fat percentage via BIA. Fat-free mass, muscle and fat mass, and fat-to-muscle ratio (FMR) differed significantly compared to the reference group. Non-ambulators showed a higher median body fat mass percentage (25.9% vs. 17.8%, = 0.01) and FMR (0.92 vs. 0.44, = 0.003) in comparison to the community walkers.

CONCLUSIONS

In SB children, BIA-measured fat mass is a better obesity indicator than BMI. Non-ambulatory, SB patients with obesity had the highest FMR values, indicating a higher risk for metabolic syndrome.

摘要

背景

患有脊柱裂（SB）的儿童肥胖风险较高，这就需要精确的方法来评估身体成分，以确保有效的体重管理。由于生长模式和骨骼结构的差异，BMI 等传统方法并不适用于这一人群。生物电阻抗分析（BIA）是一种更能准确反映身体成分的方法，但在 SB 儿童中的应用仍未得到充分探索。

方法

本研究纳入了 57 名 SB 儿童和 28 名健康对照者，中位年龄为 11 岁，评估了包括 BMI 和 BIA 衍生指标在内的人体测量学指标。Hoffer 量表用于评估 SB 儿童的身体活动水平。

结果

结果显示，32%的 SB 患者根据 BMI 被归类为超重或肥胖，而 62%的患者通过 BIA 显示出高体脂百分比。与参考组相比，无辅助步行者的去脂体重、肌肉和脂肪量以及脂肪与肌肉比（FMR）差异显著。与社区步行者相比，非辅助步行者的体脂百分比中位数（25.9% vs. 17.8%， = 0.01）和 FMR（0.92 vs. 0.44， = 0.003）更高。