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在抑郁患者中,冲动性和绝望感通过抑郁对自杀意念的连续中介作用。

Serial mediation of the relationship between impulsivity and suicidal ideation by depression and hopelessness in depressed patients.

机构信息

School of Teacher Education, Weifang University, Shandong, China.

School of Economics and Management, Shandong Vocational College of Information Technology, Shandong, China.

出版信息

BMC Public Health. 2023 Jul 31;23(1):1457. doi: 10.1186/s12889-023-16378-0.

Abstract

BACKGROUND

Close relationships have been observed among impulsivity, depression, hopelessness, and suicidal ideation in depressed patients. However, the precise mechanism that connects these psychological symptoms remains unclear. This study aims to explore the mediation effect of depression and hopelessness on the relationship between impulsivity and suicidal ideation in depressed patients.

METHODS

A total of 258 depressed patients were evaluated using the Hamilton Depression Scale, the Beck Hopelessness Scale, the Scale for Suicide Ideation, and the Barratt Impulsiveness Scale. A path analysis was afterwards performed to determine the specified relationships in the proposed model.

RESULTS

The relationship between impulsivity and suicidal ideation was found to be serially mediated by depression and hopelessness. The mediating effect of depression and hopelessness accounted for 26.59% of the total effect. Specifically, in the pathway from impulsivity to hopelessness, the mediating effect of depression accounted for 40.26%. Moreover, the relationship between impulsivity and suicidal ideation was mediated by hopelessness, with the mediating effect accounting for 12.41%. It is important to note that these relationships were observed to be independent of age and marital status. Furthermore, the proposed model demonstrated a good fit with the data.

CONCLUSIONS

This study identified a serial mediation pathway between impulsivity and suicidal ideation, mediated by depression and hopelessness. Our findings indicate that impulsivity indirectly influences suicidal ideation through its association with depression, which subsequently contributes to feelings of hopelessness. These results emphasize the importance of addressing symptoms of depression and hopelessness in the prevention and intervention efforts targeting individuals with depression. Additionally, monitoring and addressing impulsivity levels may also be crucial in reducing the risk of suicidal ideation among this population. These findings provide valuable insights for future preventive programs and interventions aimed at mitigating suicidal ideation in individuals with depression.

摘要

背景

在抑郁患者中,冲动、抑郁、绝望和自杀意念之间存在密切关系。然而,连接这些心理症状的确切机制尚不清楚。本研究旨在探讨抑郁和绝望对抑郁患者冲动与自杀意念之间关系的中介作用。

方法

共评估 258 例抑郁患者,采用汉密尔顿抑郁量表、贝克绝望量表、自杀意念量表和巴瑞特冲动量表。随后进行路径分析,以确定所提出模型中的特定关系。

结果

发现冲动与自杀意念之间的关系依次受到抑郁和绝望的中介。抑郁和绝望的中介效应占总效应的 26.59%。具体来说,在冲动到绝望的途径中,抑郁的中介效应占 40.26%。此外,冲动与自杀意念之间的关系通过绝望来介导,中介效应占 12.41%。需要注意的是,这些关系独立于年龄和婚姻状况。此外,所提出的模型与数据拟合良好。

结论

本研究确定了冲动和自杀意念之间存在抑郁和绝望的序列中介途径。我们的发现表明,冲动通过与抑郁的关联间接影响自杀意念,而抑郁又导致绝望感。这些结果强调了在针对抑郁个体的预防和干预措施中,关注抑郁和绝望症状的重要性。此外,监测和处理冲动水平在降低该人群自杀意念风险方面也可能至关重要。这些发现为未来针对抑郁个体的预防计划和干预措施提供了有价值的见解,以减轻自杀意念的发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e25/10388524/58d72f4c853a/12889_2023_16378_Fig4_HTML.jpg

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