Melbourne Eye Vet, Mulgrave, Victoria, Australia.
Sydney School of Veterinary Science, Sydney University, Camperdown, New South Wales, Australia.
Vet Ophthalmol. 2024 May;27(3):228-237. doi: 10.1111/vop.13138. Epub 2023 Aug 1.
To assess whether gonioscopy performed on Samoyed puppies (6-14 weeks of age) is a reliable predictor of their gonioscopy results as adults (>11 months of age).
A retrospective medical record search was performed to identify Samoyed dogs that had undergone gonioscopy as a puppy (6-14 weeks of age). A second prospective gonioscopy examination was performed as an adult (>11 months of age) and the results were compared. Gonioscopy was assessed on two characteristics: percent of iridocorneal angle (ICA) unaffected by pectinate ligament abnormalities (PLA) and ICA width, with PLA results categorized into unaffected ( 75% open), moderately affected (50%-74% open), and severely affected (<50% open) and the width categorized into wide, moderate, narrow, and closed groups. A multivariate model was created that considered factors such as PLA, angle width, sex, puppy age, neuter status, and time between examinations.
The eyes of 77 Samoyed dogs (154 eyes) met inclusion criteria. When assessing PLA, 90% of dogs had the same categorization as a puppy and as an adult. When assessing ICA width, 53.2% of dogs had the same width classification as a puppy and as an adult. There is strong evidence that variation between puppy and adult results increases with time between examination (p = .03).
Puppies unaffected by PLA and with a wide ICA angle, are likely to retain these features as adults. Selection of puppies with desirable gonioscopic traits may help breeders to choose dogs likely to retain these traits as adults for breeding. This may reduce the incidence of glaucoma in the breed. Puppy examinations should be performed in both eyes. Examination of adults prior to breeding remains prudent.
评估对 6-14 周龄萨摩耶幼犬进行房角镜检查是否可作为其成年（>11 月龄）时房角镜检查结果的可靠预测指标。
对接受过幼犬（6-14 周龄）房角镜检查的萨摩耶犬进行回顾性病历检索。对成年犬（>11 月龄）进行第二次前瞻性房角镜检查，并对结果进行比较。房角镜检查评估了两个特征：不受睫状突异常（PLA）影响的虹膜角膜角（ICA）百分比和 ICA 宽度，PLA 结果分为不受影响（75%开放）、中度影响（50%-74%开放）和严重影响（<50%开放），并将宽度分为宽、中、窄和闭区间。建立了一个多变量模型，考虑了 PLA、角度宽度、性别、幼犬年龄、绝育状态和检查之间的时间等因素。
77 只萨摩耶犬（154 只眼）的眼部符合纳入标准。在评估 PLA 时，90%的犬在幼犬和成年时的分类相同。在评估 ICA 宽度时，53.2%的犬在幼犬和成年时的宽度分类相同。有强有力的证据表明，检查之间的时间间隔增加会导致幼犬和成年结果之间的差异增大（p = .03）。
不受 PLA 影响且 ICA 角度较宽的幼犬，成年时很可能保留这些特征。选择具有理想房角镜特征的幼犬可能有助于饲养者选择成年后可能保留这些特征的犬进行繁殖。这可能会降低该品种青光眼的发病率。应同时对双眼进行幼犬检查。在繁殖前对成年犬进行检查仍然是谨慎的。
