School of Nursing, Beijing University of Chinese Medicine, Beijing, China.
Worldviews Evid Based Nurs. 2023 Dec;20(6):593-609. doi: 10.1111/wvn.12669. Epub 2023 Aug 1.
As pharmacotherapy often leads to adverse reactions, mind-body exercise (MBE) treatments have become a more popular option for treating depression in people living with breast cancer (BC). However, the most effective type of MBE treatment for this population remains unclear.
The aim of this systematic review and network meta-analysis (NMA) was to compare the efficacy of the different MBE modes for depression in people with BC.
A systematic search for randomized controlled trials (RCTs) from inception to March 25, 2023, was conducted in the following database: EMBASE, PubMed, Web of Science, Cochrane Library, China National Knowledge Infrastructure, Wanfang Data, China Biology Medicine, OpenGrey, and ClinicalTrials.gov. A traditional meta-analysis was conducted using the random-effects model to directly assess the effectiveness of various MBE interventions. Stata 16.0 software was used for performing the NMA.
The NMA was performed in 32 eligible RCTs including 2361 participants. The efficacy of MBE treatments on depression was ranked as the following: Liuzijue (surface under the cumulative ranking curve [SUCRA] = 95.4%) > Tai chi (SUCRA = 76.9%) > yoga (SUCRA = 55.0%) > Baduanjin (SUCRA = 53.9%) > Pilates (SUCRA = 38.6%) > dance (SUCRA = 30.2%) > Qigong (SUCRA = 28.1%) > control (SUCRA = 21.9%).
Our research showed that Liuzijue and Tai chi might be the most significantly effective MBE intervention for mitigating depression among BC survivors. Healthcare professionals could consider recommending Liuzijue and Tai Chi as a complementary therapy for BC survivors who experience depression.
由于药物治疗常常会导致不良反应，身心锻炼（MBE）治疗已成为治疗乳腺癌（BC）患者抑郁的一种更受欢迎的选择。然而，对于这一人群最有效的 MBE 治疗类型仍不清楚。
本系统评价和网络荟萃分析（NMA）的目的是比较不同 MBE 模式治疗 BC 患者抑郁的疗效。
从研究开始到 2023 年 3 月 25 日，我们在以下数据库中进行了系统搜索：EMBASE、PubMed、Web of Science、Cochrane 图书馆、中国国家知识基础设施、万方数据、中国生物医学文献数据库、OpenGrey 和 ClinicalTrials.gov。使用随机效应模型进行传统荟萃分析，直接评估各种 MBE 干预的效果。Stata 16.0 软件用于进行 NMA。
对 32 项符合条件的 RCT 进行了 NMA，共纳入 2361 名参与者。MBE 治疗对抑郁的疗效排名如下：六字诀（累积排序曲线下面积 [SUCRA] = 95.4%）>太极拳（SUCRA = 76.9%）>瑜伽（SUCRA = 55.0%）>八段锦（SUCRA = 53.9%）>普拉提（SUCRA = 38.6%）>舞蹈（SUCRA = 30.2%）>气功（SUCRA = 28.1%）>对照组（SUCRA = 21.9%）。
我们的研究表明，六字诀和太极拳可能是缓解 BC 幸存者抑郁最有效的 MBE 干预措施。医疗保健专业人员可以考虑推荐六字诀和太极拳作为 BC 幸存者的补充治疗方法，这些患者患有抑郁症。
