Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Istanbul University-Cerrahpasa, Büyükçekmece Yerleşkesi Alkent 2000 Mah. Yiğittürk Cad. No:5/9/1 Büyükçekmece, Istanbul, Turkey.
Department of Physiotherapy and Rehabilitation, Institute of Graduate Studies, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Acta Neurol Belg. 2022 Dec;122(6):1433-1446. doi: 10.1007/s13760-022-02070-4. Epub 2022 Sep 2.
Several studies have investigated the effect of mind-body exercise (MBE) on functional performance and health-related quality of life (HRQoL) in Parkinson's disease (PD), but it is still very difficult for clinicians to make informed decision on the best mind-body exercise for PD.
We analyzed the relative efficacy of MBE (yoga, Tai-Chi, Pilates, Qigong, and dance) in improving functional performance and HRQoL in patients with PD.
A systematic review of randomized controlled trials (RCTs) was performed using network meta-analysis (NMA), searching the following databases: Cochrane, Web of Science, and PubMed using specific keywords until December 28, 2021, assessing the effects of MBE on functional performance and HRQoL in patients with PD.
This review included 60 RCTs with 2037 participants. A ranking of MBE for modifying various aspects of functional performance and HRQoL was achieved. Pairwise NMA showed Pilates to be the most effective in improving functional mobility (MD: - 3.81; 95% CI (- 1.55, - 6.07) and balance performance (SMD: 2.83; 95% CI (1.87, 3.78). Yoga (MD: - 5.95; 95% CI (- 8.73, - 3.16) and dance (MD: - 5.87; 95% CI (- 8.73, - 3.01) to be the most effective in improving motor function, whereas Qigong (MD: 0.32; 95% CI (0.00, 0.64) was most effective in improving gait speed. Considering HRQoL, dance was found to be the most effective (SMD: - 0.36; 95% CI (- 0.70, -0.01).
MBE should be considered an effective strategy for improving functional performance and HRQoL in patients with PD. The most effective MBE intervention varied with the functional performance domain. Dance was an effective exercise for improving HRQoL among people with PD.
CRD42022301030.
多项研究调查了身心锻炼（MBE）对帕金森病（PD）患者的功能表现和健康相关生活质量（HRQoL）的影响，但临床医生仍然很难就 PD 最佳身心锻炼做出明智决策。
我们分析了 MBE（瑜伽、太极、普拉提、气功和舞蹈）在改善 PD 患者功能表现和 HRQoL 方面的相对疗效。
使用网络荟萃分析（NMA）对随机对照试验（RCT）进行系统评价，使用特定关键词搜索 Cochrane、Web of Science 和 PubMed 数据库，直至 2021 年 12 月 28 日，评估 MBE 对 PD 患者功能表现和 HRQoL 的影响。
本综述纳入了 60 项 RCT 共 2037 名参与者。对 MBE 改善各种功能表现和 HRQoL 方面的疗效进行了排序。两两 NMA 显示，普拉提在改善功能性移动（MD：-3.81；95%CI（-1.55，-6.07）和平衡表现（SMD：2.83；95%CI（1.87，3.78）方面最有效。瑜伽（MD：-5.95；95%CI（-8.73，-3.16）和舞蹈（MD：-5.87；95%CI（-8.73，-3.01）在改善运动功能方面最有效，而气功（MD：0.32；95%CI（0.00，0.64）在改善步态速度方面最有效。考虑 HRQoL，舞蹈被发现是最有效的（SMD：-0.36；95%CI（-0.70，-0.01）。
MBE 应被视为改善 PD 患者功能表现和 HRQoL 的有效策略。最有效的 MBE 干预措施因功能表现领域而异。舞蹈是改善 PD 患者 HRQoL 的有效运动。
PROSPERO 注册号：CRD42022301030。
