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在兔股骨骨缺损模型中,外固定器辅助钢板接骨术似乎是一种可行且可重复的手术技术:一项骨替代物研究的初步见解。

External fixator-assisted plating osteosynthesis in a rabbit model of femoral bone defects appears to be a feasible and reproducible surgical technique: preliminary insights from a bone substitute study.

作者信息

Vandenbulcke F, Anzillotti G, Ravasio G, Malagoli E, Conte P, Balzarini B, Kirienko A, Kon E

机构信息

Department of Biomedical Sciences, Humanitas University, Via Manzoni 113, Rozzano, 20089, Milan, Italy.

Humanitas Clinical and Research Center, External Fixation Unit (Dr Kirienko A), Via Manzoni 56, Rozzano, 20089, Milan, Italy.

出版信息

J Exp Orthop. 2023 Aug 1;10(1):77. doi: 10.1186/s40634-023-00644-6.

Abstract

PURPOSE

The aims of this study were to assess the complications associated with the use of an external fixator-assisted plate osteosynthesis technique to stabilize a femoral bone defect in a rabbit model and to evaluate if this technique could avoid the mispositioning and the displacement of the femoral fragments during the surgical procedure.

METHODS

A preliminary cadaveric animal study was conducted to develop a new technique of external fixator-assisted plating. Thirty rabbits underwent a surgical procedure consisting in the creation of a femoral bone defect and, subsequently an implantation of a bone substitute through the assistance of a temporary external fixator. The fixator's ability to maintain length and alignment during surgery was documented. All intraoperative complications were prospectively collected.

RESULTS

No complications related to the use of the temporary external fixator were reported. The technique successfully prevented mispositioning and dislocation during plating in all the rabbits.

CONCLUSION

In a rabbit animal model, the use of an external fixator-assisted plate osteosynthesis technique appears to be feasible and effective in avoiding misposition and rotation of femoral fragments when performing osteotomy and plating to create a mid-diaphyseal femoral defect.

摘要

目的

本研究旨在评估在兔模型中使用外固定器辅助钢板接骨术技术稳定股骨骨缺损相关的并发症,并评估该技术能否在手术过程中避免股骨碎片的错位和移位。

方法

进行了一项初步的尸体动物研究,以开发一种外固定器辅助钢板接骨的新技术。30只兔子接受了一项手术,包括制造股骨骨缺损,随后在临时外固定器的辅助下植入骨替代物。记录了固定器在手术过程中保持长度和对线的能力。前瞻性收集了所有术中并发症。

结果

未报告与使用临时外固定器相关的并发症。该技术成功地防止了所有兔子在钢板固定过程中的错位和脱位。

结论

在兔动物模型中,当进行截骨术和钢板固定以制造股骨干中段缺损时,使用外固定器辅助钢板接骨术技术在避免股骨碎片的错位和旋转方面似乎是可行且有效的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4432/10393914/68816e5b03e6/40634_2023_644_Fig1_HTML.jpg

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