Espigol Requesens D, Sarto Soliva J, Alonso Martínez I, Tallada Serra M, Boronat Rom M, Roig Quilis M
An Esp Pediatr. 1986 Aug;25(2):101-4.
A previously healthy five years old boy, following a mild nonspecific upper respiratory infection developed, fever (39 degrees C), vomiting, clouding of consciousness and focal seizures. The CSF showed a mononuclear cell reaction with negative bacterial and viral cultures. A cranial CT scan on the 4th day of admission showed bilateral low density lesions on the basal ganglia region. After 30 days of severe involvement of muscle tone (rigidity) which kept the patient immobilized in bed and without a meaningful communication with his surroundings, improvement was noticed. A repeated CT scan 40 days after admission, was considered normal. Two months after the beginning of disease, patient's physical examination was normal. This case shows striking clinical and radiological similarities to the ones described by Aicardi and Goutieres in 1982 and most likely is explained by bilateral basal ganglia edema complicating viral encephalitis. Mumps virus, being so far, the most commonly implicated.
一名此前健康的5岁男孩,在经历轻度非特异性上呼吸道感染后,出现发热(39摄氏度)、呕吐、意识模糊和局灶性癫痫发作。脑脊液显示单核细胞反应,细菌和病毒培养均为阴性。入院第4天的头颅CT扫描显示基底节区双侧低密度病变。在严重肌张力障碍(强直)30天后,患者卧床不起,与周围环境无法进行有意义的交流,之后病情有所改善。入院40天后的重复CT扫描被认为正常。疾病开始两个月后,患者的体格检查正常。该病例在临床和影像学上与1982年Aicardi和Goutieres描述的病例有显著相似之处,很可能是由病毒性脑炎并发双侧基底节水肿所致。腮腺炎病毒是迄今为止最常见的病因。