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顽固性镰刀菌真菌性眼内炎:玻璃体切除术联合病灶内注射伏立康唑和聚维酮碘的新型手术技术

Recalcitrant Fusarium Fungal Endophthalmitis: Novel Surgical Technique Combining Vitrectomy with Intralesional Injection of Voriconazole and Povidone Iodine.

作者信息

Malbin Brett, Guest John-Michael, Lin Xihui

机构信息

Kresge Eye Institute, Wayne State University, Detroit, Michigan.

出版信息

Retin Cases Brief Rep. 2023 Jul 25. doi: 10.1097/ICB.0000000000001456.

DOI:10.1097/ICB.0000000000001456
PMID:37527498
Abstract

PURPOSE

To show the feasibility while comparing functional and anatomical outcomes of vitrectomy combined with intralesional injection of voriconazole and povidone iodine for recalcitrant fusarium fungal endophthalmitis.

METHODS

In a noncomparative interventional case, vitrectomy combined with intralesional injection of voriconazole and povidone iodine was performed in a single patient.

RESULTS

Following vitrectomy and intralesional injection, our patient's fungal endophthalmitis stabilized and vision improved to 20/25. He did not require further intravitreal injections or vitrectomy.

CONCLUSIONS

Vitrectomy and intralesional injection for the treatment of refractory filamentary fungal endophthalmitis proved to be safe and effective for this case.

摘要

目的

比较玻璃体切除术联合病灶内注射伏立康唑和聚维酮碘治疗难治性镰刀菌性真菌性眼内炎时功能和解剖学结果,以证明其可行性。

方法

在一个非对照性介入病例中,对一名患者实施了玻璃体切除术联合病灶内注射伏立康唑和聚维酮碘。

结果

玻璃体切除和病灶内注射后,该患者的真菌性眼内炎病情稳定,视力提高到20/25。他无需进一步的玻璃体内注射或玻璃体切除术。

结论

对于该病例,玻璃体切除术和病灶内注射治疗难治性丝状真菌性眼内炎被证明是安全有效的。

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