Homerton Fertility Centre, Homerton University Hospital, London, UK.
Department of Reproductive Medicine, Queen Mary University of London, London, UK.
Hum Fertil (Camb). 2023 Dec;26(5):1179-1184. doi: 10.1080/14647273.2022.2152741. Epub 2023 Aug 1.
Obesity is an emerging global epidemic with a negative impact on fertility. Almost all guidelines and policies have a stringent limit of body mass index (BMI) to access fertility services which has promoted a debate amongst fertility practitioners globally. Proponents of placing such a limit point to the negative impact of elevated BMI on the outcome of fertility treatment, its cost effectiveness and the risk it poses to the intending mother and unborn child. Opponents of placing a restriction base their arguments on the lack of conclusive, robust evidence regarding the variables along with the ethical dilemmas of promoting discrimination and stigmatization by denying a couple their basic right of parenthood. In this review, we analyse these medical and ethical dilemmas in the light of current evidence. The focus is on female infertility.
肥胖是一种正在全球蔓延的流行疾病,对生育能力有负面影响。几乎所有的指南和政策都对接受生育服务的患者设定了严格的体重指数(BMI)限制,这在全球范围内引发了生育从业者的争论。支持设定这一限制的观点认为,BMI 升高对生育治疗结果、成本效益以及对计划怀孕的母亲和未出生婴儿的风险有负面影响。反对设定限制的观点则基于缺乏关于各种变量的明确、有力的证据,以及通过拒绝夫妇享有生育权来促进歧视和污名化所带来的伦理困境。在这篇综述中,我们根据现有证据分析了这些医学和伦理困境。重点是女性不孕。