Kaye Leah, Sueldo Carolina, Engmann Lawrence, Nulsen John, Benadiva Claudio
Center for Advanced Reproductive Services, Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Connecticut Health Center, Farmington, Connecticut.
Center for Advanced Reproductive Services, Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Connecticut Health Center, Farmington, Connecticut.
Fertil Steril. 2016 Mar;105(3):703-706.e2. doi: 10.1016/j.fertnstert.2015.11.035. Epub 2015 Dec 12.
To determine what assisted reproductive technologies (ART) policies, if any, have been instituted in response to an increasingly overweight and obese patient population.
Cross-sectional survey.
University-affiliated IVF clinic.
PATIENT(S): Women in the overweight and obese body mass index (BMI) categories seeking ART treatments.
INTERVENTION(S): Anonymous survey sent to medical directors at 395 IVF centers listed in Society for Assisted Reproductive Technology database.
MAIN OUTCOME MEASURE(S): Assessment of recommendations, policies, and restrictions for patients who are overweight/obese and who desire treatment for infertility, including in IVF, IUI, and donor egg cycles.
RESULT(S): Seventy-seven anonymous responses were received (19.5% response rate): 64.9% of centers have a formal policy for obesity, and 84% of those have a maximum BMI at which they will perform IVF, while 38% of those have a maximum BMI for performing IUI; 64.6% of respondents reported anesthesia requirements/concerns as the primary criteria for patient exclusion. Other primary considerations included safety during ongoing pregnancy and ART outcomes.
CONCLUSION(S): Centers that have policies regarding obesity and access to ART consider efficacy, procedural safety, safety in pregnancy, and overall health status. Policies vary widely. The patient's autonomy must be balanced with nonmaleficence and the avoidance of interventions that may be unsafe both immediately and long term.
确定针对日益增多的超重和肥胖患者群体制定了哪些辅助生殖技术(ART)政策(若有)。
横断面调查。
大学附属医院的体外受精诊所。
寻求ART治疗的超重和肥胖体重指数(BMI)类别的女性。
向辅助生殖技术协会数据库中列出的395个体外受精中心的医学主任发送匿名调查问卷。
评估针对超重/肥胖且希望治疗不孕症患者(包括体外受精、子宫内人工授精和供卵周期)的建议、政策和限制。
收到77份匿名回复(回复率19.5%):64.9%的中心有肥胖相关的正式政策,其中84%的中心有进行体外受精的BMI上限,38%的中心有进行子宫内人工授精的BMI上限;64.6%的受访者报告称麻醉要求/担忧是排除患者的主要标准。其他主要考虑因素包括孕期安全性和ART结局。
制定了肥胖及ART准入政策的中心会考虑疗效、操作安全性、孕期安全性和整体健康状况。政策差异很大。必须在患者的自主权与不伤害原则之间取得平衡,并避免可能在近期和长期都不安全的干预措施。