Wu Yunyun, Rytkin Eric, Bimrose Miles, Li Shupeng, Choi Yeon Sik, Lee Geumbee, Wang Yue, Tang Lichao, Madrid Micah, Wickerson Grace, Chang Jan-Kai, Gu Jianyu, Zhang Yamin, Liu Jiaqi, Tawfick Sameh, Huang Yonggang, King William P, Efimov Igor R, Rogers John A
Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL, 60208, USA.
Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.
Small. 2023 Dec;19(49):e2305017. doi: 10.1002/smll.202305017. Epub 2023 Aug 1.
Eco/bioresorbable electronics represent an emerging class of technology defined by an ability to dissolve or otherwise harmlessly disappear in environmental or biological surroundings after a period of stable operation. The resulting devices provide unique capabilities as temporary biomedical implants, environmental sensors, and related systems. Recent publications report schemes to overcome challenges in fabrication that follow from the low thermostability and/or high chemical reactivity of the eco/bioresorbable constituent materials. Here, this work reports the use of high-speed sewing machines, as the basis for a high-throughput manufacturing technique that addresses many requirements for these applications, without the need for high temperatures or reactive solvents. Results demonstrate that a range of eco/bioresorbable metal wires and polymer threads can be embroidered into complex, user-defined conductive patterns on eco/bioresorbable substrates. Functional electronic components, such as stretchable interconnects and antennas are possible, along with fully integrated systems. Examples of the latter include wirelessly powered light-emitting diodes, radiofrequency identification tags, and temporary cardiac pacemakers. These advances add to a growing range of options in high-throughput, automated fabrication of eco/bioresorbable electronics.
生态/生物可吸收电子器件是一类新兴技术，其定义为在经过一段稳定运行期后，能够在环境或生物环境中溶解或以其他方式无害地消失。由此产生的器件作为临时生物医学植入物、环境传感器及相关系统具有独特的功能。最近的出版物报道了一些方案，以克服由于生态/生物可吸收组成材料的低热稳定性和/或高化学反应性而在制造过程中面临的挑战。在此，本研究报告了使用高速缝纫机作为高通量制造技术的基础，该技术满足了这些应用的许多要求，且无需高温或反应性溶剂。结果表明，一系列生态/生物可吸收金属线和聚合物线可以绣制在生态/生物可吸收基板上，形成复杂的、用户定义的导电图案。诸如可拉伸互连和天线等功能性电子元件是可行的，同时还能实现完全集成的系统。后者的例子包括无线供电的发光二极管、射频识别标签和临时心脏起搏器。这些进展为生态/生物可吸收电子产品的高通量、自动化制造增加了越来越多的选择。
