Department of Otolaryngology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Department of Otolaryngology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China;Institute of Hearing and Speech-Language Science, Xinhua College of Sun Yat-sen University, Guangzhou, China
J Int Adv Otol. 2023 Jul;19(4):311-317. doi: 10.5152/iao.2023.221009.
Patulous eustachian tube is a disorder that leads to disturbing symptoms such as autophony, respiratory noise, and aural fullness. There has not been an established treatment found for this disorder. This study aims to assess the efficacy of autologous fat injection for a novel treatment of patients with patulous eustachian tube.
Twenty-eight patients with refractory patulous eustachian tube were recruited for the study. Endoscopic autologous fat injection was performed submucosally into the anterior and posterior portion of the pharyngeal orifice of the eustachian tube. The outcomes were quantitatively assessed by comparing the difference between pre- and postoperative scores with the visual analog scale on 4 criteria: aural fullness, respiratory noise, tinnitus, and autophony.
Autologous fat injection was performed successfully in all patients without major complications. According to the combined visual analog scale scores, after the treatments, 20 patients showed significant improvement and 6 showed moderate improvement. The overall success rate of the treatment was 92.9%.
Autologous fat injection is an effective and safe procedure for the treatment of patulous eustachian tube.
咽鼓管异常开放是一种导致自声增强、呼吸音、耳闷等不适症状的疾病，但目前尚无明确的治疗方法。本研究旨在评估自体脂肪注射治疗咽鼓管异常开放的疗效。
本研究共纳入 28 例难治性咽鼓管异常开放患者，在内镜下将自体脂肪经黏膜下注射至咽鼓管咽口的前、后部位。通过视觉模拟量表（VAS）对 4 项指标（耳闷、呼吸音、耳鸣和自声增强）的术前和术后评分差值进行定量评估，以评估疗效。
所有患者均成功完成自体脂肪注射，无严重并发症。根据综合 VAS 评分，治疗后 20 例患者显著改善，6 例患者中度改善，总有效率为 92.9%。
自体脂肪注射是治疗咽鼓管异常开放的一种有效且安全的方法。
