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恶性黑色素瘤的细胞形态学谱:印度一家三级医疗中心的3年研究

Cytomorphological Spectrum of Malignant Melanoma: A 3-Year Study in a Tertiary Care Centre in India.

作者信息

Kaur Ashmeet, Hemrajani Deepika, Harsh Anita, Vijay Urvashi, Wadhwani Deepa

机构信息

From the Department of Pathology, SMS Medical College, Jaipur, Rajasthan, India.

Multidisciplinary Research Unit (MDRU), Research Scientist, MDRU, SMS Medical College, Jaipur, Rajasthan, India.

出版信息

Indian J Dermatol. 2023 May-Jun;68(3):257-260. doi: 10.4103/ijd.ijd_548_22.

Abstract

BACKGROUND

Melanoma is an aggressive malignant tumor with high metastatic potential. FNAC provides a quick and effective tool to diagnose primary and metastatic melanoma cases.

AIMS AND OBJECTIVES

To document the epidemiological features of malignant melanoma cases attending in a tertiary care centre in India, with special reference to different cytomorphological parameters.

MATERIALS AND METHODS

This was a retrospective hospital based study done in the Department of Pathology. 39 cases of malignant melanoma diagnosed on cytology during a period of 3 years were retrieved, reviewed and studied.

RESULTS

Out of the 39 cases,21 were males(1.16 male:female ratio). The mean age was 53 years. Metastatic cases were more common than primary melanoma cases. Most common site for metastasis was liver followed by inguinal lymph node. Epitheloid was the most common pattern.

CONCLUSION

Characterstic melanin pigment although common, is not always present. Thus, cytopathologists must know the various cytomorphological spectrum of features of melanoma.

摘要

背景

黑色素瘤是一种具有高转移潜能的侵袭性恶性肿瘤。细针穿刺抽吸活检(FNAC)为诊断原发性和转移性黑色素瘤病例提供了一种快速有效的工具。

目的

记录在印度一家三级医疗中心就诊的恶性黑色素瘤病例的流行病学特征,特别提及不同的细胞形态学参数。

材料与方法

这是一项在病理学系进行的基于医院的回顾性研究。检索、回顾并研究了3年内经细胞学诊断的39例恶性黑色素瘤病例。

结果

39例病例中,男性21例(男女比例为1.16:1)。平均年龄为53岁。转移性病例比原发性黑色素瘤病例更常见。最常见的转移部位是肝脏,其次是腹股沟淋巴结。上皮样是最常见的模式。

结论

特征性黑色素虽然常见,但并非总是存在。因此,细胞病理学家必须了解黑色素瘤特征的各种细胞形态学谱。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f690/10389121/1d42112093ba/IJD-68-257-g001.jpg

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