Dwari Binayak Chandra, Patro Nibedita, Bhatt Mamata, Tripathy Nalini
From the Department of Dermatology, Hitech Hospital, Bhubaneswar, Odisha, India.
Department of Microbiology, Hitech Hospital, Bhubaneswar, Odisha, India.
Indian J Dermatol. 2023 May-Jun;68(3):245-250. doi: 10.4103/ijd.ijd_917_21.
Male urethritis is primarily sexually transmitted in India and has also shown a high rate. Urethritis or inflammation of the urethra is a multifactorial condition. It is called gonococcal urethritis (GU) when is detected in a urethral smear of the patient and non-gonococcal urethritis (NGU) when this organism cannot be visualized.
To study the demographic profile and management pattern of NGU retrospectively in male patients.
Urethritis cases were identified from the dermatology outpatient record. A retrospective study of data of patients diagnosed with NGU was done for 5 years from August 2015 to July 2020. We included only male patients more than 10 years of age.
(CT, 48%) was the most common causative organism found. The diagnosis was confirmed by demonstrating ≥5 polymorphonuclear lymphocytes (PMNLs) from the anterior urethra using a Gram-stained urethral smear followed by the polymerase chain reaction (PCR.) of urine. The most common age group affected was 21-30, (30, 46%) years with a mean ± standard deviation (SD) of 30.32 ± 10.80. Most patients were from low socioeconomic status, labourers (36, 55%). A history of heterosexual behaviour, (57, 88%) was the most common and it had been seen that sexual exposure was more common in unmarried patients (38, 59%). Associated features were seen in 18 patients. Among recommended initial therapies for NGU, doxycycline and azithromycin might be improved by the addition of antimicrobial coverage for (). Further, it was seen that response to doxycycline therapy was better than azithromycin.
Though there is an increased incidence of Herpes infections, we found infection to be the most common cause of NGU. Doxycycline showed better results in NGU due to infection.
在印度,男性尿道炎主要通过性传播,且发病率也很高。尿道炎或尿道炎症是一种多因素疾病。当在患者尿道涂片中检测到时,称为淋菌性尿道炎(GU);当无法观察到这种病原体时,则称为非淋菌性尿道炎(NGU)。
回顾性研究男性患者非淋菌性尿道炎的人口统计学特征和管理模式。
从皮肤科门诊记录中识别尿道炎病例。对2015年8月至2020年7月期间诊断为非淋菌性尿道炎的患者数据进行了5年的回顾性研究。我们仅纳入年龄超过10岁的男性患者。
(沙眼衣原体,48%)是最常见的致病病原体。通过革兰氏染色尿道涂片从前尿道显示≥5个多形核淋巴细胞(PMNLs),随后进行尿液聚合酶链反应(PCR)来确诊。受影响最常见的年龄组是21 - 30岁,(30例,46%),平均年龄±标准差(SD)为30.32±10.80。大多数患者来自社会经济地位较低的劳动者群体(36例,55%)。异性性行为史(57例,88%)是最常见的,并且发现未婚患者的性接触更为常见(38例,59%)。18例患者出现相关特征。在推荐的非淋菌性尿道炎初始治疗中,多西环素和阿奇霉素可能通过增加对(某种病原体)的抗菌覆盖而得到改善。此外,发现多西环素治疗的反应优于阿奇霉素。
尽管疱疹感染的发病率有所增加,但我们发现(某种病原体)感染是非淋菌性尿道炎最常见的原因。由于(某种病原体)感染,多西环素在非淋菌性尿道炎中显示出更好的效果。