Department of Plastic and Reconstructive Surgery, Peking university Shenzhen hospital, Shenzhen, China.
Division of Plastic Surgery, Department of Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
J Cosmet Dermatol. 2024 Jan;23(1):90-98. doi: 10.1111/jocd.15943. Epub 2023 Aug 2.
Owing to its safety and convenience, botulinum toxin type A (BoNtA) has become a first-choice treatment for contouring calf muscle asymmetries or deformities. Different injection methods and dosages have been discussed in the literature, but a standardized BoNtA treatment remains unclear.
This study aimed to classify gastrocnemius muscle hypertrophy (GMH) through multiple measurements to provide a personalized BoNtA treatment protocol.
The measurements combining of gastrocnemius muscle (GM) contour, max leg circumference and GM thickness was applied to classify different type of GMH in a normal population. Based on these findings, a personalized BoNtA treatment protocol was determined and evaluated regarding max leg circumference, GM thickness, the position of max leg circumference, patient and doctor satisfaction rate, and complications.
A total of 100 GMH were classified into two bulging types (bilateral-bulging type and unilateral-bulging type) and two categories (moderate GMH and severe GMH). 40 cases were treated with personalized BoNtA injection methods ("Even" or "Intense"method) and dosages (300 or 400 units). Follow-up examinations at 1, 3, and 6 months after treatment. Max leg circumference and GM thickness decreased significantly and the position of max leg circumference rose prominently during treatment (2.56 1.93; p 0.05). The overall patient satisfaction rate was 70%-100%. No serious complications occurred.
We identify four groups of GMH through several measurements and outline a personalized BoNtA treatment for each type. This recommended protocol may improve the therapeutic outcomes and patient satisfaction after treatment.
由于其安全性和便利性，A型肉毒毒素（BoNtA）已成为矫正小腿肌肉不对称或畸形的首选治疗方法。文献中讨论了不同的注射方法和剂量，但标准化的 BoNtA 治疗仍不清楚。
本研究旨在通过多项测量对腓肠肌肥大（GMH）进行分类，为个性化 BoNtA 治疗方案提供依据。
结合测量腓肠肌（GM）轮廓、最大小腿周长和 GM 厚度，对正常人群中不同类型的 GMH 进行分类。基于这些发现，确定了个性化 BoNtA 治疗方案，并对最大小腿周长、GM 厚度、最大小腿周长的位置、患者和医生的满意度以及并发症进行了评估。
共对 100 例 GMH 进行分类，分为两种隆起型（双侧隆起型和单侧隆起型）和两类（中度 GMH 和重度 GMH）。40 例采用个性化 BoNtA 注射方法（“均匀”或“强烈”方法）和剂量（300 或 400 单位）进行治疗。治疗后 1、3 和 6 个月进行随访检查。最大小腿周长和 GM 厚度明显下降，最大小腿周长的位置明显升高（2.56±1.93;p<0.05）。整体患者满意度为 70%-100%。无严重并发症发生。
我们通过多项测量确定了四组 GMH，并为每种类型制定了个性化的 BoNtA 治疗方案。该推荐方案可能会提高治疗后的疗效和患者满意度。
