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肉毒杆菌毒素注射治疗腓肠肌肥大并进行磁共振成像评估和三维评价

Treatment of Gastrocnemius Muscle Hypertrophy with Botulinum Toxin Injection Followed by Magnetic Resonance Imaging Assessment and 3-Dimensional Evaluation.

作者信息

Bogari Melia, Tan Andy, Xin Yu, Chai Gang, Lin Li, Min Peiru, Zhang Yan, Zhang Yixin

机构信息

Department of Plastic and Reconstructive Surgery, Shanghai 9th People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P.R. China.

出版信息

Aesthet Surg J. 2017 Oct 16;37(10):1146-1156. doi: 10.1093/asj/sjx070.

DOI:10.1093/asj/sjx070
PMID:29040400
Abstract

BACKGROUND

Hypertrophy of the gastrocnemius muscle is considered to be a hindrance to lower leg beauty in the Asian aesthetic market. A noninvasive technique that has been gaining recognition involves botulinum toxin A injection; however, there are no proper guidelines or standardized protocols for the administration of botulinum toxin to correct gastrocnemius hypertrophy.

OBJECTIVES

This study sought to determine the most effective botulinum toxin injection method for correcting the contour of the lower leg calf, as well as to determine the dose that can produce the maximum effect in meeting the demands of the physician and patient.

METHODS

Eighteen female patients aged between 18 and 35 years were enrolled in this study from January 2015 to July 2015. Two injection methods were compared: (I) 48 injection points with a distance of 2 cm between every point; and (II) 10 injection points. Magnetic resonance imaging examinations were conducted at baseline prior to treatment and at one month and 6 months after treatment. A 3-dimensional study was performed to analyze the volumetric changes.

RESULTS

The most effective and significant treatment method for hypertrophic gastrocnemius muscle was the 48-point method (scattering injection). Following injection, this method exhibited a significant level of satisfaction with outcome.

CONCLUSIONS

Our study reveals that injection dosage and method have a strong relationship with achieving a better contouring result.

LEVEL OF EVIDENCE

摘要

背景

在亚洲审美市场中,腓肠肌肥大被认为是影响小腿美观的因素。一种逐渐获得认可的非侵入性技术是注射A型肉毒毒素;然而,对于使用肉毒毒素矫正腓肠肌肥大,尚无适当的指南或标准化方案。

目的

本研究旨在确定矫正小腿轮廓最有效的肉毒毒素注射方法,并确定能在满足医生和患者需求方面产生最大效果的剂量。

方法

2015年1月至2015年7月,18名年龄在18至35岁之间的女性患者纳入本研究。比较两种注射方法:(I)48个注射点,各点间距2厘米;(II)10个注射点。在治疗前基线、治疗后1个月和6个月进行磁共振成像检查。进行三维研究以分析体积变化。

结果

对于肥厚性腓肠肌,最有效且显著的治疗方法是48点法(分散注射)。注射后,该方法对结果的满意度较高。

结论

我们的研究表明,注射剂量和方法与获得更好的塑形效果密切相关。

证据级别

3级。

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Plast Reconstr Surg Glob Open. 2024 May 20;12(5):e5813. doi: 10.1097/GOX.0000000000005813. eCollection 2024 May.
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Plast Reconstr Surg Glob Open. 2023 Oct 30;11(10):e5356. doi: 10.1097/GOX.0000000000005356. eCollection 2023 Oct.
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A Double-Blinded, Randomized, Dose-Comparison Pilot Study to Comparatively Evaluate Efficacy and Safety of Two Doses of Botulinum Toxin Type A Injection for Deltoid Muscle Hypertrophy.
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Ann Dermatol. 2023 Oct;35(5):355-359. doi: 10.5021/ad.22.155.
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Am J Transl Res. 2023 Jul 15;15(7):4962-4969. eCollection 2023.
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