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基于乳腺癌特定生物学行为的治疗

[Treatment of breast cancer based on its specific biological behavior].

作者信息

Tominaga T

出版信息

Gan To Kagaku Ryoho. 1986 Sep;13(9):2718-25.

PMID:3753020
Abstract

Breast cancer is one of the types of malignant tumor which have hormonal dependency and anti-tumor treatments utilizing this characteristic are widely performed. ER-positive breast cancer responds well to ablative surgery or administration of anti-estrogenic compounds. In contrast, high-dose administration of estrogen is also effective in postmenopausal patients. Inflammatory breast cancer is a rapidly growing and spreading type of tumor and for these types of cancers preoperative chemo-endocrine therapy is effective. However, the prognosis of cases with liver metastases is not good and therapeutic methods for such patients should be investigated.

摘要

乳腺癌是具有激素依赖性的恶性肿瘤类型之一,利用这一特性的抗肿瘤治疗被广泛应用。雌激素受体阳性的乳腺癌对根治性手术或抗雌激素化合物的给药反应良好。相比之下,高剂量雌激素给药对绝经后患者也有效。炎性乳腺癌是一种快速生长和扩散的肿瘤类型,对于这类癌症,术前化疗 - 内分泌治疗是有效的。然而,有肝转移的病例预后不佳,应研究针对此类患者的治疗方法。

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